Evidence map›Paper›PMID 34532062›Full record

ArticleVirus evolution2021

Integrating animal movements with phylogeography to model the spread of PRRSV in the USA.

Dennis N Makau, Moh A Alkhamis, Igor A D Paploski, Cesar A Corzo, Samantha Lycett, Kimberly VanderWaal

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Dennis N MakauDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.
Moh A AlkhamisDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Health Sciences Center, Kuwait University, Kuwait City, 24923, Safat 13110, Kuwait.
Igor A D PaploskiDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.
Cesar A CorzoDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.
Samantha LycettRoslin Institute, University of Edinburgh, Edinburgh, Midlothian, EH25 9RG, UK.ORCID https://orcid.org/0000-0003-3159-596X
Kimberly VanderWaalDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Minneapolis, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.
University of Minnesota · USKuwait University · KWRoslin Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral sequence data coupled with phylodynamic models have become instrumental in investigating the outbreaks of human and animal diseases, and the incorporation of the hypothesized drivers of pathogen spread can enhance the interpretation from phylodynamic inference. Integrating animal movement data with phylodynamics allows us to quantify the extent to which the spatial diffusion of a pathogen is influenced by animal movements and contrast the relative importance of different types of movements in shaping pathogen distribution. We combine animal movement, spatial, and environmental data in a Bayesian phylodynamic framework to explain the spatial diffusion and evolutionary trends of a rapidly spreading sub-lineage (denoted L1A) of porcine reproductive and respiratory syndrome virus (PRRSV) Type 2 from 2014 to 2017. PRRSV is the most important endemic pathogen affecting pigs in the USA, and this particular virulent sub-lineage emerged in 2014 and continues to be the dominant lineage in the US swine industry to date. Data included 984 open reading frame 5 (ORF5) PRRSV L1A sequences obtained from two production systems in a swine-dense production region (∼85,000 mi

Indexed as

animal movementBayesian inferencelivestock networksmolecular epidemiologyphylodynamic modelsphylogeography

Identifiers

PMID34532062
PMCPMC8438914
OpenAlexW3167785615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.