Evidence map›Paper›PMID 34531949›Full record

ArticleACS medicinal chemistry letters2021

Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity.

Juliana da Silva Pacheco, Débora de Souza Costa, Edézio Ferreira Cunha-Júnior, Valter Viana Andrade-Neto, Alan H Fairlamb, Susan Wyllie, Marília O F Goulart, Danyelle C Santos, Thaissa L Silva, Marina A Alves and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Forging a Future Free from Neglected Tropical Diseases.ACS medicinal chemistry letters · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Juliana da Silva PachecoFIOCRUZ, Instituto Oswaldo Cruz, Laboratório de Bioquímica de Tripanosomatídeos, Rio de Janeiro, RJ, Brazil.
Débora de Souza CostaUniversidade Federal do Rio de Janeiro, Instituto de Pesquisas de Produtos Naturais, Laboratório de Química Bioorgânica, Rio de Janeiro, RJ, Brazil.
Edézio Ferreira Cunha-JúniorFIOCRUZ, Instituto Oswaldo Cruz, Laboratório de Bioquímica de Tripanosomatídeos, Rio de Janeiro, RJ, Brazil.
Valter Viana Andrade-NetoFIOCRUZ, Instituto Oswaldo Cruz, Laboratório de Bioquímica de Tripanosomatídeos, Rio de Janeiro, RJ, Brazil.
Alan H FairlambUniversity of Dundee, School of Life Sciences, Division of Biological Chemistry and Drug Discovery, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom.
Susan WyllieUniversity of Dundee, School of Life Sciences, Division of Biological Chemistry and Drug Discovery, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom.ORCID https://orcid.org/0000-0001-8810-5605
Marília O F GoulartUniversidade Federal de Alagoas, Instituto de Química e Biotecnologia, Maceió, AL, Brazil.
Danyelle C SantosUniversidade Federal de Alagoas, Instituto de Química e Biotecnologia, Maceió, AL, Brazil.
Thaissa L SilvaUniversidade Federal de Alagoas, Núcleo de Ciências Exatas, Campus de Arapiraca, Arapiraca, AL, Brazil.
Marina A AlvesUniversidade Federal do Rio de Janeiro, Laboratório de Apoio ao Desenvolvimento Tecnológico, Rio de Janeiro, RJ, Brazil.
Paulo R R CostaUniversidade Federal do Rio de Janeiro, Instituto de Pesquisas de Produtos Naturais, Laboratório de Química Bioorgânica, Rio de Janeiro, RJ, Brazil.
Ayres G DiasUniversidade do Estado do Rio de Janeiro, Centro de Tecnologia e Ciências, Departamento de Química Orgânica, Rio de Janeiro, RJ, Brazil.
Eduardo Caio Torres-SantosFIOCRUZ, Instituto Oswaldo Cruz, Laboratório de Bioquímica de Tripanosomatídeos, Rio de Janeiro, RJ, Brazil.ORCID https://orcid.org/0000-0003-2240-4519
Fundação Oswaldo Cruz · BRUniversidade Federal de Alagoas · BRUniversidade Federal do Rio de Janeiro · BRUniversity of Dundee · GBUniversidade do Estado do Rio de Janeiro · BR

Funding

Wellcome Trust 203134/Z/16/Z
6 · The paper itself

Abstract

5-Nitro-furan nitrones (

Identifiers

PMID34531949
PMCPMC8436238
OpenAlexW3194589663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.