Evidence map›Paper›PMID 34531920›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Mechanism of

Wang Xiang, Zhiyong Long, Jinsong Zeng, Xiaofei Zhu, Mengxia Yuan, Jiamin Wu, Yonghe Wu, Liang Liu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wang XiangThe Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Province, China.
Zhiyong LongShantou University Medical College, Shantou University, Shantou, Guangdong, China.
Jinsong ZengThe First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan Province, China.ORCID https://orcid.org/0000-0002-0622-8271
Xiaofei ZhuHunan University of Chinese Medicine, Changsha, Hunan Province, China.
Mengxia YuanShantou University Medical College, Shantou University, Shantou, Guangdong, China.
Jiamin WuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Yonghe WuHunan University of Chinese Medicine, Changsha, Hunan Province, China.
Liang LiuHunan University of Chinese Medicine, Changsha, Hunan Province, China.
Hunan University of Traditional Chinese Medicine · CNShantou University · CNGuilin Medical University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the therapeutic targets, network modules, and coexpressed genes of

methodsThe TCM database was used to predict the potential compounds of Radix Rhei Et Rhizome, and the PharmMapper was used to predict its potential targets. GeneCards and OMIM were used to search for CI-related genes. Cytoscape was used to construct a protein-protein interaction (PPI) network and to screen out core genes and detection network modules. Then, DAVID and Metascape were used for enrichment analysis. After that, in-depth analysis of the proteomics data was carried out to further explore the mechanism of

results(1) A total of 14

conclusionThis study combined network pharmacology and proteomics to explore the main material basis of

Identifiers

PMID34531920
PMCPMC8440083
OpenAlexW3197321481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.