Evidence map›Paper›PMID 34531878›Full record

ReviewFrontiers in immunology2021

Janus Kinase Inhibitors and Cell Therapy.

Amer Assal, Markus Y Mapara

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Novel strategies to manage CAR-T cell toxicity.Nature reviews. Drug discovery · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Amer AssalDepartment of Medicine, Bone Marrow Transplantation and Cell Therapy Program, Columbia University Irving Medical Center, New York, NY, United States.
Markus Y MaparaDepartment of Medicine, Bone Marrow Transplantation and Cell Therapy Program, Columbia University Irving Medical Center, New York, NY, United States.
Columbia University · USColumbia University Irving Medical Center · US

Funding

Graft Engineering of Allogeneic Hematopoietic Stem Cell Products with Molecular CascadesR01EB025221 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAPARA, MARKUS Y, STOJANOVIC, MILAN N · 2018 to 2021
$2.6M
NIBIB NIH HHS R01 EB025221
6 · The paper itself

Abstract

Cellular therapies such as allogeneic hematopoietic stem cell transplantation (HSCT) and immune-effector cell therapy (IECT) continue to have a critical role in the treatment of patients with high risk malignancies and hematologic conditions. These therapies are also associated with inflammatory conditions such as graft-

Indexed as

Hematopoietic Stem Cell TransplantationAnimalsCytokine Release SyndromeGraft vs Host DiseaseHumansJanus Kinase InhibitorsJanus KinasesSignal TransductionJanus Kinase InhibitorsJanus Kinasescell therapy (CT)cytokine release syndrome (CRS)graft-versus-host disease (GvHD)JAK - STAT signaling pathwaytransplantation

Identifiers

PMID34531878
PMCPMC8438227
OpenAlexW3197158717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.