Evidence map›Paper›PMID 34531813›Full record

ArticleFrontiers in neurology2021

Carotid Atheroinflammation Is Associated With Cerebral Small Vessel Disease Severity.

Nicholas R Evans, Jason M Tarkin, Jessica Walsh, Mohammed M Chowdhury, Andrew J Patterson, Martin J Graves, James H F Rudd, Elizabeth A Warburton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Suspected ophthalmic artery fat embolus following bilateral elbow liposuction.American journal of ophthalmology case reports · 2026
    Article
  4. Frailty and Cardiovascular Risk.European cardiology · 2026
    Review
  5. Frailty and stroke: Global implications for assessment, research, and clinical care-A WSO scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nicholas R EvansDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Jason M TarkinDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Jessica WalshDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
Mohammed M ChowdhuryDepartment of Surgery, University of Cambridge, Cambridge, United Kingdom.
Andrew J PattersonDepartment of Radiology, University of Cambridge, Cambridge, United Kingdom.
Martin J GravesDepartment of Radiology, University of Cambridge, Cambridge, United Kingdom.
James H F RuddDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Elizabeth A WarburtonDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GB

Funding

Wellcome Trust 211100/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atherosclerosisblood-brain barriercarotid arterycarotid-cerebrovascular interfacecerebrovascular disease/strokeleukoaraiosis

Identifiers

PMID34531813
PMCPMC8438317
OpenAlexW3198048434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.