Evidence map›Paper›PMID 34531649›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2021

The Relationship Between Dry Eye Disease and Digital Screen Use.

Zaina Al-Mohtaseb, Scott Schachter, Bridgitte Shen Lee, Jaclyn Garlich, William Trattler

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06288945 (Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome), which is not on this map. Cited by 76 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 7 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06288945 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome

TypeinterventionalSponsorAlexandria UniversityRan2023 to 2023Enrolled60ConditionsDry Eye SyndromeArmsEducational Program
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 7 syntheses or guidelines pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Immediate Effects of Light Mode and Dark Mode Features on Visual Fatigue in Tablet Users.International journal of environmental research and public health · 2025
    Trial
  9. Trial
  10. Observational
  11. Dynamic Tear Film Stability Assessed via an Open-View Double-Pass Imaging System.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Zaina Al-MohtasebDepartment of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA.
Scott SchachterPresbyopia and Ocular Surface Disease, Allergan, an AbbVie Company, Irvine, CA, USA.
Bridgitte Shen LeeVision Optique, Houston, TX, USA.
Jaclyn GarlichEnvision Optometry, Boston, MA, USA.ORCID 0000-0002-9230-5092
William TrattlerCenter for Excellence in Eye Care, Miami, FL, USA.
AbbVie (United States) · USBaylor College of Medicine · USCenter for Excellence in Eye Care · USNew England College of Optometry · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dry eye disease is characterized by tear film instability that can result in ocular surface damage. Patients with dry eye disease may experience ocular pain/discomfort and visual disturbances that may negatively impact quality of life. Increased use of digital screens for work, communication, and entertainment, especially during times of pandemic, may contribute to dry eye. Extensive cross-sectional studies have shown that digital screen use duration is associated with an increased risk of severe symptoms and clinical diagnosis of dry eye disease in adults. Smartphone use duration has also been found to be greater in school-age children with dry eye disease than in those without dry eye disease. A commonly accepted hypothesis for the relationship between digital screen use and dry eye disease is that digital screen use changes blinking dynamics, leading to ocular dryness. This review describes evidence that digital screen use is associated with dry eye disease, that digital device use alters blinking dynamics, and that dry eye affects mental health and work productivity in digital screen users. Helpful prevention and management strategies for dry eye disease exist for those who use digital screens.

Indexed as

blinkingcomputerocular surfacequality of lifesmartphonevisual display

Identifiers

PMID34531649
PMCPMC8439964
OpenAlexW3199274633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.