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ArticleMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents2021

Benzopyrylium salts as new anticancer, antibacterial, and antioxidant agents.

Swayamsiddha Kar, Abdul Akhir, Sidharth Chopra, Shinya Ohki, Balasubramanyam Karanam, Nageswara Rao Golakoti

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Anticancer Activity ofBiomolecules · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Swayamsiddha KarDepartment of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Andhra Pradesh 515134, India.
Abdul AkhirDivision of Microbiology, CSIR-Central Drug Research Institute, Lucknow 226031 Uttar Pradesh, India.
Sidharth ChopraDivision of Microbiology, CSIR-Central Drug Research Institute, Lucknow 226031 Uttar Pradesh, India.
Shinya OhkiCenter for Nano Materials and Technology, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa 923-1211, Japan.
Balasubramanyam KaranamDepartment of Biology and Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.
Nageswara Rao GolakotiDepartment of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Andhra Pradesh 515134, India.
Central Drug Research Institute · INSri Sathya Sai Institute of Higher Learning · INJapan Advanced Institute of Science and Technology · JPTuskegee University · US

Funding

Tuskegee University Center for Biomedical Research/ Research Centers at Minority InstitutionsU54MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI Jason Anthony White · 2017 to 2026
$29.4M
NIMHD NIH HHS U54 MD007585
6 · The paper itself

Abstract

Benzopyrylium salts are an unexplored class of compounds and as a first, this study reports them as potential therapeutic agents. In this effort we pursue the synthesis and in vitro anticancer, antibacterial and antioxidant properties of some novel benzopyrylium salts. The benzopyrylium salts were synthesized and further characterized via UV-vis, IR,

Indexed as

Antibacterial activityAnticancer activityAntioxidant activityBenzopyrylium saltsSynthesis

Identifiers

PMID34531644
PMCPMC8443163
OpenAlexW3121060165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.