Evidence map›Paper›PMID 34531454›Full record

ArticleScientific reports2021

Children and adolescents with neurodevelopmental disorders show cognitive heterogeneity and require a person-centered approach.

María Elena Márquez-Caraveo, Rocío Rodríguez-Valentín, Verónica Pérez-Barrón, Ruth Argelia Vázquez-Salas, José Carlos Sánchez-Ferrer, Filipa De Castro, Betania Allen-Leigh, Eduardo Lazcano-Ponce

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  8. Observational
  9. Review
  10. The Use of Compounds Derived fromInternational journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Neurodiversity in elite sport: a systematic scoping review.BMJ open sport & exercise medicine · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Heterogeneity of Cognitive Profiles in Children and Adolescents with Mild Intellectual Disability (MID).International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María Elena Márquez-CaraveoChildren's Psychiatric Hospital Juan N. Navarro, Av. San Fernando 86, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.ORCID 0000-0001-5438-3009
Rocío Rodríguez-ValentínReproductive Health Division, Center for Population Health Research, National Institute of Public Health, Av. Universidad No. 655, Col. Santa María Ahuacatitlán, 62100, Cuernavaca, Morelos, Mexico. rocio.rodriguez@insp.mx.ORCID 0000-0002-8917-3420
Verónica Pérez-BarrónChildren's Psychiatric Hospital Juan N. Navarro, Av. San Fernando 86, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico. veronicaperezbarron@gmail.com.
Ruth Argelia Vázquez-SalasCONACYT, Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.ORCID 0000-0002-9333-1671
José Carlos Sánchez-FerrerCenter for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.ORCID 0000-0003-1330-3775
Filipa De CastroReproductive Health Division, Center for Population Health Research, National Institute of Public Health, Av. Universidad No. 655, Col. Santa María Ahuacatitlán, 62100, Cuernavaca, Morelos, Mexico.ORCID 0000-0001-5072-657X
Betania Allen-LeighReproductive Health Division, Center for Population Health Research, National Institute of Public Health, Av. Universidad No. 655, Col. Santa María Ahuacatitlán, 62100, Cuernavaca, Morelos, Mexico. ballen@insp.mx.ORCID 0000-0002-9097-2553
Eduardo Lazcano-PonceAcademic Secretariat, School of Public Health of Mexico, National Institute of Public Health, Cuernavaca, Morelos, Mexico.ORCID 0000-0003-1259-6369

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to identify patterns of cognitive differences and characterize subgroups of Mexican children and adolescents with three neurodevelopmental disorders (NDD): intellectual disability (ID), autism spectrum disorders (ASD) and attention deficit/hyperactivity disorder (ADHD). The sample included 74 children and adolescents 6-15 years; 34% had ID, ASD or ADHD, 47% had ID in comorbidity with ASD, ADHD or both, 11% had ASD + ADHD, 8% were children without NDD. We applied WISC-IV, Autism Diagnostic Interview-Revised, Mini-International Neuropsychiatric Structured Interview, Child Behavior Checklist, and UNICEF Child Functioning Module. We evaluated the normality of the WISC-IV sub-scales using the Shapiro-Francia test, then conducted a latent class analysis and assessed inter-class differences in terms of household, parent and child characteristics. The following four-class solution best fit the data: "Lower Cognitive Profile" (LCP), "Lower Working Memory" (LWM), "Higher Working Memory" (HWM), "Higher Cognitive Profile" (HCP). LCP included most of the children with ID, who had a low Working Memory (WM) index score. LWM included mainly children with ASD or ID + ADHD; their Perceptual Reasoning (PR) and Processing Speed (PS) index scores were much higher than those for Verbal Comprehension (VC) and WM. HWM included children with ASD or ADHD; their scores for PR, PS and VC were high with lower WM (although higher than for LWM). HCP included children without NDD and with ASD or ADHD or both and had the highest scores on all indices. Children with NDD show cognitive heterogeneity and thus require individualized treatment plans.

Indexed as

CognitionAdolescentBiological Variation, PopulationChildDevelopmental DisabilitiesFemaleHumansIntelligence TestsMale

Identifiers

PMID34531454
PMCPMC8445997

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.