Evidence map›Paper›PMID 34531450›Full record

ArticleScientific reports2021

Evaluation of endothelial function and subclinical atherosclerosis in patients with HIV infection.

F Arnaiz de Las Revillas, V Gonzalez-Quintanilla, J A Parra, E Palacios, C Gonzalez-Rico, C Armiñanzas, M Gutiérrez-Cuadra, A Oterino, C Fariñas-Alvarez, M C Fariñas

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Progression of subclinical cardiovascular disease in patients with HIV.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

F Arnaiz de Las Revillas *Infectious Diseases Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Av. Valdecilla s/n, 39008, Santander, Spain.ORCID 0000-0002-0611-6309
V Gonzalez-QuintanillaNeurology Service, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
J A Parra *Radiology Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
E PalaciosNeurology Service, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
C Gonzalez-RicoInfectious Diseases Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Av. Valdecilla s/n, 39008, Santander, Spain.
C Armiñanzas *Infectious Diseases Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Av. Valdecilla s/n, 39008, Santander, Spain.
M Gutiérrez-CuadraInfectious Diseases Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Av. Valdecilla s/n, 39008, Santander, Spain.
A OterinoNeurology Service, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
C Fariñas-Alvarez *Quality Unit. Hospital Universitario Marqués de Valdecilla-IDIVAL, Santander, Spain.
M C FariñasInfectious Diseases Service, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Av. Valdecilla s/n, 39008, Santander, Spain. mcarmen.farinas@scsalud.es.
Universidad de Cantabria · ESMarqués de Valdecilla University Hospital · ESInstituto de Investigación Marqués de Valdecilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to analyse the association between human immunodeficiency virus (HIV) related clinical and analytical parameters and the presence of subclinical atherosclerosis as well as endothelial dysfunction. This was a prospective cohort study of HIV-positive patients who underwent intima media thickness (IMT) determination and coronary artery calcium scoring to determine subclinical atherosclerosis. To detect endothelial dysfunction, the breath holding index, flow-mediated dilation and the concentration of endothelial progenitor cells (EPCs) were measured. Patients with an IMT ≥ 0.9 mm had an average of 559.3 ± 283.34 CD4/μl, and those with an IMT < 0.9 mm had an average of 715.4 ± 389.92 CD4/μl (p = 0.04). Patients with a low calcium score had a significantly higher average CD4 cell value and lower zenith viral load (VL) than those with a higher score (707.7 ± 377.5 CD4/μl vs 477.23 ± 235.7 CD4/μl (p = 0.01) and 7 × 10

Indexed as

AdultAgedAtherosclerosisBreath HoldingCoronary VesselsEndothelial Progenitor CellsEndothelium, VascularFemaleHIV InfectionsHumansMaleMiddle AgedVasodilation

Identifiers

PMID34531450
PMCPMC8446055
OpenAlexW3201533558

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.