Observational studyScientific reports2021
COVID-19 patients age, comorbidity profiles and clinical presentation related to the SARS-CoV-2 UK-variant spread in the Southeast of France.
Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed.
- Advancing health equity in wastewater-based epidemiology: A global critical review and conceptual framework.SSM - population health · 2025Review
- Antibiotic Usage and Healthcare-AssociatedAntibiotics (Basel, Switzerland) · 2025Article
- Comparative Study of the Mutations Observed in the SARS-CoV-2 RBD Variants of Concern and Their Impact on the Interaction with the ACE2 Protein.The journal of physical chemistry. B · 2023Article
- Predictors of Liver Injury in Hospitalized Patients with SARS-CoV-2 Infection.Medicina (Kaunas, Lithuania) · 2022Article
- Health system impacts of SARS-CoV - 2 variants of concern: a rapid review.BMC health services research · 2022Review
- Detecting SARS-CoV-2 lineages and mutational load in municipal wastewater and a use-case in the metropolitan area of Thessaloniki, Greece.Scientific reports · 2022Article
- The ins and outs of SARS-CoV-2 variants of concern (VOCs).Archives of virology · 2022Review
- SARS-CoV-2 Variants and Clinical Outcomes: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- Emerging SARS-CoV-2 Variants of Concern (VOCs): An Impending Global Crisis.Biomedicines · 2021Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (Southeast of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this area. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits. We performed an observational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n = 1247) and those hospitalized in the infectious diseases ward or ICU (n = 232). The UK-variant was absent in this area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63 to 50% (p = 0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p < 0.001) while the proportion of patients without comorbidity increased from 16 to 42% (p = 0.007). Spread of the UK-variant in the Southeast of France affects younger and healthier patients.
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