Evidence map›Paper›PMID 34531276›Full record

ArticleThe European respiratory journal2021

Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing.

Kosuke Kato, Yoon-Joo Shin, Sunny Palumbo, Ioannis Papageorgiou, Seongmin Hahn, Joseph D Irish, Skye P Rounseville, Robert T Krafty, Lutz Wollin, Maor Sauler and 1 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kosuke KatoDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, Emory University, Atlanta, GA, USA.ORCID 0000-0001-9758-3262
Yoon-Joo ShinDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, Emory University, Atlanta, GA, USA.
Sunny PalumboDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, University of Arizona, Tucson, AZ, USA.
Ioannis PapageorgiouDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, Emory University, Atlanta, GA, USA.
Seongmin HahnDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, University of Arizona, Tucson, AZ, USA.
Joseph D IrishDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, University of Arizona, Tucson, AZ, USA.
Skye P RounsevilleDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, University of Arizona, Tucson, AZ, USA.
Robert T KraftyDept of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Lutz WollinBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Maor SaulerDept of Medicine, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5240-7978
Louise HeckerDivision of Pulmonary, Allergy and Critical Care and Sleep Medicine, Dept of Medicine, Emory University, Atlanta, GA, USA louise.hecker@emory.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Role of MIF and CD74 in the pathogenesis of emphysemaR01HL155948 · NHLBI · YALE UNIVERSITY · PI BUCALA, RICHARD J, SAULER, MAOR · 2021 to 2025
$3.4M
MIF and DNA repair in the emphysematous lungK08HL135402 · NHLBI · YALE UNIVERSITY · PI SAULER, MAOR · 2017 to 2021
$842k
Preclinical development of a novel Nrf2-activator formulation for the treatment of idiopathic pulmonary fibrosisR21AG054766 · NIA · UNIVERSITY OF ARIZONA · PI HECKER, LOUISE, MANSOUR, HEIDI M. · 2017 to 2018
$415k
The role of Nampt in age-associated persistent lung fibrosisI01BX003919 · VA · VETERANS HEALTH ADMINISTRATION · PI HECKER, LOUISE · 2018 to 2022
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BLRD VA I01 BX003919NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K08 HL135402NHLBI NIH HHS R01 HL155948NIA NIH HHS R21 AG054766
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Idiopathic Pulmonary FibrosisIndolesAgingHumansProtein Kinase InhibitorsIndolesnintedanibProtein Kinase Inhibitors

Identifiers

PMID34531276
PMCPMC8613836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.