Evidence map›Paper›PMID 34531241›Full record

ArticleBMJ case reports2021

Multisystem inflammatory syndrome in children (MIS-C) occurring in temporal proximity between siblings.

Lina Lim, Sheau Jen Lim, Jia Shyi Loy, David Ce Ng

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lina LimDepartment of Paediatric Intensive Care, Hospital Melaka, Melaka, Malaysia.
Sheau Jen LimDepartment of Paediatrics, Hospital Melaka, Melaka, Malaysia.
Jia Shyi LoyDepartment of Paediatrics, Hospital Melaka, Melaka, Malaysia.
David Ce NgDepartment of Paediatrics, Hospital Tuanku Ja'afar Seremban, Seremban, Malaysia davidngce@gmail.com.ORCID http://orcid.org/0000-0001-9665-3054
Malacca General Hospital · MYHospital Tuanku Ja’afar · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a pair of siblings who developed multisystem inflammatory syndrome in children (MIS-C) in close temporal proximity after recent exposure to SARS-CoV-2. Both siblings presented with Kawasaki disease-like features and haemodynamic instability, with the onset of symptoms within 6 days of each other. Remarkably, one of the siblings was the elder of a pair of monozygotic twins. The younger monozygotic twin, however, did not develop MIS-C.

Indexed as

COVID-19AgedChildHumansSARS-CoV-2SiblingsSystemic Inflammatory Response SyndromeCOVID-19paediatric intensive care

Identifiers

PMID34531241
PMCPMC8449949
OpenAlexW3200036977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.