Evidence map›Paper›PMID 34531235›Full record

ArticleBMJ case reports2021

Buschke-Löwenstein tumour: a rare and challenging entity.

Carlos Eduardo Costa Almeida, José Azevedo, Inês Botelho, Jaime Vilaça

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Biocompatible hydrogel eradicates pregnancy-associated genital warts.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  3. Article
  4. Article
  5. Local excision for anal squamous cell carcinoma: challenges in patient selection and diagnosis.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Article
  6. Buschke-Löwenstein Tumor: An Unusual Therapeutic Approach.GE Portuguese journal of gastroenterology · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carlos Eduardo Costa AlmeidaGeneral Surgery, Hospital da Luz, Aveiro, Portugal carloscostaalmeida@yahoo.com.ORCID http://orcid.org/0000-0002-3541-9974
José AzevedoGeneral Surgery, Hospital da Horta EPER, Horta, Portugal.
Inês BotelhoGeneral Surgery Consultation Nurse, Hospital da Luz, Vila Nova de Gaia, Portugal.
Jaime VilaçaGeneral Surgery, Hospital da Luz, Vila Nova de Gaia, Portugal.
Hospital da Luz · PTCompanhia União Fabril · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buschke-Löwenstein tumour (BLT) is rare and locally aggressive, and malignant transformation is a possibility. Because there is no consensus on the best treatment approach, the authors present a treatment algorithm based on several case reports. A 57-year-old male patient resorted to surgical consultation with a giant perianal cauliflower-like mass. A BLT was diagnosed. Due to the involvement of the anal sphincter, a wide local excision saving the rectum failed. Abdominoperineal resection was performed. Malignant transformation was diagnosed, and adjuvant radiotherapy was delivered. Clinical evolution was uneventful. Aggressive behaviour despite the absence of malignancy is the hallmark of BLT. The common presentation is an anal mass with a cauliflower-like appearance. Anal verrucous carcinoma and squamous cell carcinoma are the major differential diagnoses. BLT treatment is challenging. Surgery is the first-line treatment, raging from wide local excision to abdominoperineal resection. To improve outcomes, chemoradiation can be used in combination with surgery. Long-term follow-up is mandatory.

Indexed as

Anus NeoplasmsBuschke-Lowenstein TumorCarcinoma, Squamous CellCarcinoma, VerrucousAnal CanalHumansMaleMiddle Ageddermatologygeneral surgeryhuman papilloma virus

Identifiers

PMID34531235
PMCPMC8449944
OpenAlexW3199432805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.