Evidence map›Paper›PMID 34530908›Full record

SynthesisWorld journal of emergency surgery : WJES2021

Anorectal emergencies: WSES-AAST guidelines.

Antonio Tarasconi, Gennaro Perrone, Justin Davies, Raul Coimbra, Ernest Moore, Francesco Azzaroli, Hariscine Abongwa, Belinda De Simone, Gaetano Gallo, Giorgio Rossi and 34 more

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in World journal of emergency surgery : WJES, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07295886 (Observational Study on the Use of Topical Nifedipine 0.3% and Lidocaine 1.5% in Acute Uncomplicated Hemorrhoidal Disease), which is not on this map. Cited by 49 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07295886 recruitingnot on this mapstarted 2025, after this paper: background citation

Observational Study on the Use of Topical Nifedipine 0.3% and Lidocaine 1.5% in Acute Uncomplicated Hemorrhoidal Disease

Typeobservational_patient_registrySponsorCardarelli HospitalRan2025 to 2026Enrolled80ConditionsHemorrhoid Bleeding, Hemorrhoids Prolapse, Hemorrhoid Pain, HemorrhoidArmstopical nifedipine 0.3% plus lidocaine 1.5%
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Treatment method selection for perianal abscesses: bedside or operating room? a single center, retrospective study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Testicular endocrine function recovers following Fournier's gangrene.American journal of clinical and experimental urology · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Antonio TarasconiEmergency Surgery Department, Parma University Hospital, Parma, Italy. atarasconi@gmail.com.ORCID 0000-0001-6588-2268
Gennaro PerroneEmergency Surgery Department, Parma University Hospital, Parma, Italy.
Justin DaviesCambridge Colorectal Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Raul CoimbraRiverside University Health System Medical Center, Loma Linda University School of Medicine, Riverside, CA, USA.
Ernest MooreErnest E. Moore Shock Trauma Center at Denver Health, Denver, CO, USA.
Francesco AzzaroliGastroenterology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Hariscine AbongwaEmergency Surgery Department, Parma University Hospital, Parma, Italy.
Belinda De SimoneDepartment of Metabolic, Digestive and Emergency Surgery, Centre Hospitalier Intercommunal de Poissy et Saint Germain en Laye, Poissy, France.
Gaetano GalloDepartment of Medical and Surgical Sciences, University of Catanzaro, Catanzaro, Italy.
Giorgio RossiEmergency Surgery Department, Parma University Hospital, Parma, Italy.
Fikri Abu-ZidanDepartment of Surgery, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates.
Vanni AgnolettiAnesthesia and Intensive Care Unit, AUSL Romagna, M.Bufalini Hospital, Cesena, Italy.
Gianluigi de'AngelisDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Nicola de'AngelisMinimally Invasive and Robotic Digestive Surgery Unit, Regional General Hospital F. Miulli, Bari, Ital - Université Paris Est, UPEC, Creteil, France.
Luca AnsaloniDepartment of Emergency and general Surgery, Pavia University Hospital, Pavia, Italy.
Gian Luca BaiocchiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Paolo CarcoforoDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Marco CeresoliGeneral Surgery, Monza University Hospital, Monza, Italy.
Alain Chichom-MefireFaculty of Health Sciences, Department of Surgery, University of Buea, Buea, Cameroon.
Salomone Di SaverioGeneral surgery 1st unit, Department of General Surgery, University of Insubria, Varese, Italy.
Federica GaianiDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Mario GiuffridaDepartment of Medicine and Surgery, General Surgery Unit, University Hospital of Parma, Parma, Italy.
Andreas HeckerDepartment of General & Thoracic Surgery, University Hospital of Giessen, Giessen, Germany.
Kenji InabaDivision of Acute Care Surgery, University of Southern California, Los Angeles, CA, USA.
Michael KellyDepartment of General Surgery, Albury Hospital, Albury, Australia.
Andrew KirkpatrickGeneral, Acute Care, Abdominal Wall Reconstruction, and Trauma Surgery, Foothills Medical Centre, Calgary, Alberta, Canada.
Yoram KlugerDivision of General Surgery, Rambam Health Care Campus, Haifa, Israel.
Ari LeppäniemiHelsinki University Hospital, Helsinki, Finland.
Andrey LitvinDepartment of Surgical Disciplines, Regional Clinical Hospital, Immanuel Kant Baltic Federal University, Kaliningrad, Russia.
Carlos OrdoñezDepartment of Surgery, Fundacion Valle del Lili - Universidad del Valle, Cali, Colombia.
Vittoria PattonieriEmergency Surgery Department, Parma University Hospital, Parma, Italy.
Andrew PeitzmanUniversity of Pittsburgh School of Medicine, UPMC-Presbyterian, Pittsburgh, PA, USA.
Manos Pikoulis3rd Department of Surgery, National & Kapodistrian University of Athens, Athens, Greece.
Boris SakakushevGeneral Surgery Department, University Hospital St George, Plovdiv, Bulgaria.
Massimo SartelliDepartment of Surgery, Macerata Hospital, Macerata, Italy.
Vishal ShelatDepartment of Surgery, Tan Tock Seng Hospital, Singapore, Singapore.
Edward TanDepartment of Surgery, Department of Emergency Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Mario TestiniAcademic Unit of General Surgery "V. Bonomo" Department of Biomedical Sciences and Human Oncology, University of Bari, Bari, Italy.
George VelmahosDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA, USA.
Imtiaz WaniGovernment Gousia Hospital, Srinagar, Kashmir, India.
Dieter WeberDepartment of General Surgery, Royal Perth Hospital, University of Western Australia, Perth, Australia.
Walter BifflDepartment of Trauma and Acute Care Surgery, Scripps Memorial Hospital La Jolla, La Jolla, San Diego, CA, USA.
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy.
Fausto CatenaGeneral, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anorectal emergencies comprise a wide variety of diseases that share common symptoms, i.e., anorectal pain or bleeding and might require immediate management. While most of the underlying conditions do not need inpatient management, some of them could be life-threatening and need prompt recognition and treatment. It is well known that an incorrect diagnosis is frequent for anorectal diseases and that a delayed diagnosis is related to an impaired outcome. This paper aims to improve the knowledge and the awareness on this specific topic and to provide a useful tool for every physician dealing with anorectal emergencies.The present guidelines have been developed according to the GRADE methodology. To create these guidelines, a panel of experts was designed and charged by the boards of the World Society of Emergency Surgery (WSES) and American Association for the Surgery of Trauma (AAST) to perform a systematic review of the available literature and to provide evidence-based statements with immediate practical application. All the statements were presented and discussed during the WSES-AAST-WJES Consensus Conference on Anorectal Emergencies, and for each statement, a consensus among the WSES-AAST panel of experts was reached. We structured our work into seven main topics to cover the entire management of patients with anorectal emergencies and to provide an up-to-date, easy-to-use tool that can help physicians and surgeons during the decision-making process.

Indexed as

EmergenciesRectal DiseasesHumansUnited StatesAngiographyAnorectal bleedingAnorectal foreign bodiesAnorectal sepsisAnorectal VaricesAntibioticsDiagnosisEmbolizationFournier’s gangreneGuidelinesHemorrhoidsNon-operative managementSurgeryTechniqueTiming

Identifiers

PMID34530908
PMCPMC8447593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.