Evidence map›Paper›PMID 34530757›Full record

ArticleBMC neurology2021

Clinical significance of stroke nurse in patients with acute ischemic stroke receiving intravenous thrombolysis.

Zhao-Han Xu, Qi-Wen Deng, Qian Zhai, Qing Zhang, Zhen-Jie Wang, Wen-Xia Chen, Meng-Meng Gu, Teng Jiang, Jun-Shan Zhou, Ying-Dong Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhao-Han Xu *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Qi-Wen Deng *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Qian Zhai *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Qing ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Zhen-Jie WangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Wen-Xia ChenDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Meng-Meng GuDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China.
Teng JiangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China. jt870918@163.com.
Jun-Shan ZhouDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China. zhjsh333@126.com.
Ying-Dong ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China. zhangyingdong@njmu.edu.cn.

Funding

Natural Science Foundation of Jiangsu Province BK20201117
6 · The paper itself

Abstract

backgroundReports have proven that shorter door-to-needle time (DTN time) indicates better outcomes in AIS patients received intravenous thrombolysis. Efforts have been made by hospitals and centers to minimize DTN time in many ways including introducing a stroke nurse. However, there are few studies to discuss the specific effect of stroke nurse on patients' prognosis. This study aimed to compare consecutive AIS patients before and after the intervention to analyze the effect of stroke nurse on clinical outcome of AIS patients.

methodsIn this retrospective study, we observed 1003 patients from November 2016 to December 2020 dividing in two groups, collected and analyzed AIS patients' medical history, clinical assessment information, important timelines, 90 mRS score, etc. Comparative analysis and mediation analysis were also used in this study.

resultsA total of 418 patients was included in this study, and 199 patients were enrolled in the stroke nurse group and 219 was in the preintervention group. Baseline characteristics of patients showed no significant difference except there seems more patients with previous ischemic stroke history in the group of stroke nurse. (p = 0.008). The median DTN time significantly decreased in the stroke nurse group (25 min versus 36 min, p < 0.001) and multivariate logistic regression analysis showed the 90-day mRS clinical outcome significantly improved in the stroke nurse group (p = 0.001). Mediation analysis indicated the reduction of DTN time plays a partial role on the 90 days mRS score and the stroke nurse has some direct effect on the improvement of clinical outcome (p = 0.006).

conclusionsThe introduction of stroke nurse is beneficial to clinical outcome of AIS patients and can be use of reference in other hospitals or centers.

Indexed as

Brain IschemiaIschemic StrokeStrokeFibrinolytic AgentsHumansRetrospective StudiesThrombolytic TherapyTime-to-TreatmentTissue Plasminogen ActivatorTreatment OutcomeFibrinolytic AgentsTissue Plasminogen ActivatorAcute ischemic strokeDoor-to-needle timeIntravenous thrombolysisStroke nurse

Identifiers

PMID34530757
PMCPMC8447702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.