Evidence map›Paper›PMID 34530746›Full record

ArticleBMC nephrology2021

Transmission of SARS-CoV-2 considering shared chairs in outpatient dialysis: a real-world case-control study.

Ravi Thadhani, Joanna Willetts, Catherine Wang, John Larkin, Hanjie Zhang, Lemuel Rivera Fuentes, Len Usvyat, Kathleen Belmonte, Yuedong Wang, Robert Kossmann and 3 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Ravi ThadhaniMass General Brigham, Boston, MA, USA.
Joanna WillettsFresenius Medical Care, Global Medical Office, 920 Winter Street, Waltham, MA, USA.
Catherine WangCarnegie Mellon University, Pittsburgh, PA, USA.
John LarkinFresenius Medical Care, Global Medical Office, 920 Winter Street, Waltham, MA, USA. John.Larkin@fmc-na.com.
Hanjie ZhangRenal Research Institute, New York, NY, USA.
Lemuel Rivera FuentesRenal Research Institute, New York, NY, USA.
Len UsvyatFresenius Medical Care, Global Medical Office, 920 Winter Street, Waltham, MA, USA.
Kathleen BelmonteFresenius Kidney Care, Waltham, MA, USA.
Yuedong WangUniversity of California-Santa Barbara, Santa Barbara, CA, USA.
Robert KossmannFresenius Medical Care North America, Medical Office, Waltham, MA, USA.
Jeffrey HymesFresenius Medical Care, Global Medical Office, 920 Winter Street, Waltham, MA, USA.
Peter KotankoRenal Research Institute, New York, NY, USA.
Franklin MadduxFresenius Medical Care AG & Co. KGaA, Global Medical Office, Bad Homburg, Germany.
Fresenius Medical Care (United States) · USRenal Research Institute · USCarnegie Mellon University · USFresenius Medical Care (Germany) · DEFresenius Medical Care North America (United States)Icahn School of Medicine at Mount Sinai · USMass General Brigham · USUniversity of California, Santa Barbara · US

Funding

Early detection, containment, and management of COVID-19 in dialysis facilities using multi-modal data sourcesR01DK130067 · NIDDK · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GUO, WENSHENG, KOTANKO, PETER · 2021 to 2023
$2.0M
Fresenius Medical Care North America NANIDDK NIH HHS R01 DK130067NIDDK NIH HHS R01DK130067
6 · The paper itself

Abstract

backgroundSARS-CoV-2 can remain transiently viable on surfaces. We examined if use of shared chairs in outpatient hemodialysis associates with a risk for indirect patient-to-patient transmission of SARS-CoV-2.

methodsWe used data from adults treated at 2,600 hemodialysis facilities in United States between February 1st and June 8th, 2020. We performed a retrospective case-control study matching each SARS-CoV-2 positive patient (case) to a non-SARS-CoV-2 patient (control) treated in the same dialysis shift. Cases and controls were matched on age, sex, race, facility, shift date, and treatment count. For each case-control pair, we traced backward 14 days to assess possible prior exposure from a 'shedding' SARS-CoV-2 positive patient who sat in the same chair immediately before the case or control. Conditional logistic regression models tested whether chair exposure after a shedding SARS-CoV-2 positive patient conferred a higher risk of SARS-CoV-2 infection to the immediate subsequent patient.

resultsAmong 170,234 hemodialysis patients, 4,782 (2.8 %) tested positive for SARS-CoV-2 (mean age 64 years, 44 % female). Most facilities (68.5 %) had 0 to 1 positive SARS-CoV-2 patient. We matched 2,379 SARS-CoV-2 positive cases to 2,379 non-SARS-CoV-2 controls; 1.30 % (95 %CI 0.90 %, 1.87 %) of cases and 1.39 % (95 %CI 0.97 %, 1.97 %) of controls were exposed to a chair previously sat in by a shedding SARS-CoV-2 patient. Transmission risk among cases was not significantly different from controls (OR = 0.94; 95 %CI 0.57 to 1.54; p = 0.80). Results remained consistent in adjusted and sensitivity analyses.

conclusionsThe risk of indirect patient-to-patient transmission of SARS-CoV-2 infection from dialysis chairs appears to be low.

Indexed as

Ambulatory Care FacilitiesInterior Design and FurnishingsOutpatientsRenal DialysisVirus SheddingAgedCase-Control StudiesCOVID-19Environmental ExposureFemaleFomitesHumansInfection ControlLogistic ModelsMaleMiddle AgedCOVID-19End Stage Renal DiseaseHemodialysisKidney FailureSARS-CoV-2

Identifiers

PMID34530746
PMCPMC8444531
OpenAlexW3201529922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.