ArticleGlobal spine journal2023
Who Needs Surgical Stabilization for Pyogenic Spondylodiscitis? Retrospective Analysis of Non-Surgically Treated Patients.
Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Publicly Accessible Large Language Model Responses to Frequently Asked Questions About Spondylodiscitis: Preliminary Expert Evaluation.Journal of medical Internet research · 2026Article
- External Validation of the SITE Score for De Novo Spinal Infections: A Retrospective Cohort Study.Global spine journal · 2026Article
- Successful treatment of pyogenic spondylitis in a non-ankylosing lesion of diffuse idiopathic skeletal hyperostosis using penetrating endplate screws: a three-case report.Journal of surgical case reports · 2025Article
- The conundrum of finding an optimal spondylodiscitis treatment pathway: how do treatments affect readmission rates?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Review
- Evaluation of the SITE score for de-novo spinal infection patients in clinical practice - A case-based approach.Brain & spine · 2025Article
- Anterior Column Reconstruction of Destructive Vertebral Osteomyelitis at the Thoracolumbar Spine with an Expandable Vertebral Body Replacement Implant: A Retrospective, Monocentric Radiological Cohort Analysis of 24 Cases.Journal of clinical medicine · 2024Article
- Midterm survival and risk factor analysis in patients with pyogenic vertebral osteomyelitis: a retrospective study of 155 cases.Frontiers in surgery · 2024Article
- Article
- The Hamburg Spondylodiscitis Assessment Score (HSAS) for Immediate Evaluation of Mortality Risk on Hospital Admission.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designRetrospective case series analysis.
objectiveTo identify relevant clinical and radiographic markers for patients presenting with infectious spondylo-discitis associated with spinal instability directly related to the infectious process.
methodsWe evaluated patients presenting with de-novo intervertebral discitis or vertebral osteomyelitis /discitis (VOD) who initiated non-surgical treatment. Patients who failed conservative treatment and required stabilization surgery within 90 days were defined as "
resultsOverall 35 patients had initiated non-surgical treatment for VOD. 25 patients had an uneventful course (NSG), while 10 patients failed conservative treatment ("FTG") within 90 days. Factors found to be associated with poorer outcome were intra-venous drug abuse (IVDA) as well as the presence of fever upon initial presentation. Radiographically, involvement of the same-level facets and the extent of caudal and rostral VB involvement in both MRI and CT were found to be significantly associated with poorer clinical and radiographic outcome.
conclusionsWe show that clinical factors such as IVDA status and fever as well as the extent of osseous and posterior element involvement may prove to be helpful in favoring surgical treatment early on in the management of spinal infections.
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Registered trials
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