ArticleInternational journal of clinical practice2021
Sex differences in electrolyte imbalances caused by SARS-CoV-2: A cross-sectional study.
Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Dysnatremia and Endocrine Alterations in Hospitalized COVID-19 Patients: Markers of Systemic Stress Rather than Independent Predictors of Outcomes.Biomedicines · 2026Article
- Plasma aldosterone is low in patients hospitalized with COVID-19 and not associated with changes in serum potassium levels:Frontiers in endocrinology · 2025Observational
- Semi-quantitative CT score reflecting the degree of pulmonary infection as a risk factor of hypokalemia in COVID-19 patients: a cross-sectional study.Frontiers in medicine · 2024Article
- The Association between Dysnatraemia during Hospitalisation and Post-COVID-19 Mental Fatigue.Journal of clinical medicine · 2023Article
- Post-COVID-19 effect on biochemical parameters in children: Should we take heed?Saudi journal of biological sciences · 2023Article
- Sex differences in electrolyte imbalances caused by SARS-CoV-2: A cross-sectional study.International journal of clinical practice · 2021Article
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16 authors.
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Abstract
backgroundSince SARS-CoV-2 spread, evidence regarding sex differences in progression and prognosis of COVID-19 have emerged. Besides this, studies on patients' clinical characteristics have described electrolyte imbalances as one of the recurrent features of COVID-19.
methodsWe performed a cross-sectional study on all patients admitted to the emergency department (ED) from 1 March to 31 May 2020 who had undergone a blood gas analysis and a nasopharyngeal swab test for SARS-CoV-2 by rtPCR. We defined positive patients as cases (n = 710) and negatives as controls (n = 619), for a total number of patients of 1.329. The study was approved by the local ethics committee Area 3 Milan. Data were automatically extracted from the hospital laboratory SQL-based repository in anonymised form. We considered as outcomes potassium (K
resultsWe observed a higher prevalence of hypokalaemia among patients positive for SARS-CoV-2 (13.7% vs 6% of negative subjects). Positive patients had a higher probability to be admitted to the ED with hypokalaemia (OR 2.75, 95% CI 1.8-4.1, P < .0001) and women were twice as likely to be affected than men (OR 2.43, 95% CI 1.67-3.54, P < .001). Odds ratios for positive patients to manifest with an alteration in serum Na
conclusionsSARS-CoV-2 infection is associated with a higher prevalence of hypokalaemia, hypocalcaemia, hypochloraemia and sodium alterations. Hypokalaemia is more frequent among women and hypocalcaemia among men.
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