Evidence map›Paper›PMID 34529833›Full record

ArticleImmunology2021

Prostaglandin E

Marie Goepp, Siobhan Crittenden, You Zhou, Adriano G Rossi, Shuh Narumiya, Chengcan Yao

Open access · hybridAbstract read
In one paragraph

Article in Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Neuroinflammation and Disease: Pathways and Opportunities.Annual review of pharmacology and toxicology · 2026
    Review
  7. Prostaglandin EProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Prostaglandin EImmunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Marie GoeppCentre for Inflammation Research, Queen's Medical Research Institute,, The University of Edinburgh, Edinburgh, UK.
Siobhan CrittendenCentre for Inflammation Research, Queen's Medical Research Institute,, The University of Edinburgh, Edinburgh, UK.
You ZhouSystems Immunity University Research Institute, and Division of Infection and Immunity, Cardiff University, Cardiff, UK.
Adriano G RossiCentre for Inflammation Research, Queen's Medical Research Institute,, The University of Edinburgh, Edinburgh, UK.
Shuh NarumiyaAlliance Laboratory for Advanced Medical Research and Department of Drug Discovery Medicine, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Chengcan YaoCentre for Inflammation Research, Queen's Medical Research Institute,, The University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-3754-2842
Queen's Medical Centre · GBInstitute of Infection and Immunity · CAKyoto University · JP

Funding

Cancer Research UK 25246Medical Research Council MR/K013386/1Medical Research Council MR/R008167/1
6 · The paper itself

Abstract

Regulatory T (Treg) cells are essential for control of inflammatory processes by suppressing effector T-cell functions. The actions of PGE

Indexed as

Signal TransductionAnimalsCell DifferentiationCells, CulturedDinoprostoneGene Expression ProfilingHumansImmunophenotypingMiceMice, TransgenicReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 SubtypeT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTransforming Growth Factor betaDinoprostoneReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 SubtypeTransforming Growth Factor betaEP receptorsFoxp3inflammationprostaglandin E2regulatory T cellTGF-β

Identifiers

PMID34529833
PMCPMC8561111
OpenAlexW3201052409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.