Evidence map›Paper›PMID 34529672›Full record

ArticlePloS one2021

HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks.

Lisie Souza Castro, Grazielli Rocha de Rezende, Fernanda Rodas Pires Fernandes, Larissa Melo Bandeira, Gabriela Alves Cesar, Barbara Vieira do Lago, Michele Soares Gomes Gouvêa, Ana R C Motta-Castro

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Severe cases of hepatitis A: case series in Curitiba, Paraná, 2023-2024.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026
    Article
  3. Article
  4. Hepatitis A, B and C prevalence among transgender women and travestis in five Brazilian capitals between 2019-2021.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lisie Souza CastroFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Grazielli Rocha de RezendeFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Fernanda Rodas Pires FernandesFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Larissa Melo BandeiraFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Gabriela Alves CesarFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Barbara Vieira do LagoLaboratory of Viral Hepatitis, Oswaldo Cruz Foundation, FIOCRUZ, Rio de Janeiro, Brazil.ORCID 0000-0002-9173-6309
Michele Soares Gomes GouvêaInstitute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Ana R C Motta-CastroFederal University of Mato Grosso do Sul, Campo Grande, Brazil.
Universidade Federal de Mato Grosso do Sul · BRFundação Oswaldo Cruz · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis A is a fecal-oral infection caused by hepatitis A virus (HAV). Men who have sex with men (MSM) and transgender women (TW) have been reported as target groups for HAV infection. This study aimed to determine the seroprevalence, risk factors, and circulating strains associated with HAV infection among MSM and TW in Central Brazil.

methodsA cross-sectional study was conducted from November 2011 to September 2013. Serum samples were collected from 425 individuals for anti-HAV antibody testing and HAV molecular characterization. Of them, 149 (35.1%) participants were self-identified as transgender women. Statistical analysis was performed to evaluate the risk factors of HAV seropositivity.

resultsThe seroprevalence of HAV exposure was 69.7% (95% Confidence Interval: 65.3-74.0%). Serological evidence of HAV was significantly higher in participants who self-identified as transgender women (83.2%) than MSM (62.3%). Increasing age, non-white race, and lower monthly household income were independently associated with HAV exposure among MSM. Only lower monthly household income was independently associated with HAV exposure among TW. One anti-HAV IgM positive sample, from a transgender woman (0.2%), was detected and classified as subgenotype IA.

conclusionsHigh HAV prevalence was observed, markedly among TW. Considering the risky sexual behaviors this population is exposed to, HAV vaccination and prevention programs targeting this population should be considered to prevent outbreaks and the burden of the disease.

Indexed as

VaccinationAdolescentAdultBrazilCross-Sectional StudiesDisease OutbreaksHepatitis AHumansMaleMiddle AgedPrevalenceRisk FactorsSeroepidemiologic StudiesSexual and Gender MinoritiesYoung Adult

Identifiers

PMID34529672
PMCPMC8445402
OpenAlexW3201137645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.