Evidence map›Paper›PMID 34529275›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2021

The impact of spectacle lenses for myopia control on visual functions.

Yi Gao, Ee Woon Lim, Adeline Yang, Björn Drobe, Mark A Bullimore

Registry-linked trialAbstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07780851 (Wearing Behavior and Short-Term Changes in Axial Length in Children With Myopia Wearing Myopia Control Spectacle Lenses), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07780851 nacompletednot on this mapstarted 2025, after this paper: background citation

Wearing Behavior and Short-Term Changes in Axial Length in Children With Myopia Wearing Myopia Control Spectacle Lenses

TypeinterventionalSponsorEssilor InternationalRan2025 to 2026Enrolled20ConditionsMyopiaArmsSingle Vision Lens (SVL), Myopia Control Lens (MCL)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. The Impact of Myopia Control Spectacle Lens Designs on Visual Function.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. IMI-Interventions for Controlling Myopia Onset and Progression 2025.Investigative ophthalmology & visual science · 2025
    Review
  12. Review
  13. Optical influence of myopia control spectacles at the retinal level: Effect of local light modulation.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  14. Article
  15. Observational
  16. Article
  17. Optical interventions for myopia control.Eye (London, England) · 2024
    Review
  18. IMI-Onset and Progression of Myopia in Young Adults.Investigative ophthalmology & visual science · 2023
    Review
  19. IMI 2023 Digest.Investigative ophthalmology & visual science · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi GaoResearch & Development, Vision Sciences AMERA, Essilor International, Singapore, Singapore.
Ee Woon LimResearch & Development, Vision Sciences AMERA, Essilor International, Singapore, Singapore.
Adeline YangResearch & Development, Vision Sciences AMERA, Essilor International, Singapore, Singapore.
Björn DrobeResearch & Development, Vision Sciences AMERA, Essilor International, Singapore, Singapore.
Mark A BullimoreCollege of Optometry, University of Houston, Houston, Texas, USA.ORCID 0000-0002-6315-3720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpectacle lenses containing multiple small peripheral elements have been developed for myopia control in children. It is important that their effect on vision be quantified by (i) fixation through the peripheral portion, thereby using foveal vision and (ii) by fixation through the central portion and presentation of peripheral targets.

methodsThe above approaches were used in five studies to evaluate two novel spectacle lens designs: spectacle lenses with Highly Aspherical Lenslets (HAL) and Slightly Aspherical Lenslets (SAL). A single vision lens served as a control. Visually normal adults participated in each study. The first two studies had subjects fixate through the periphery of the lenses. High and low (10%) contrast visual acuity was measured with the Freiburg Vision Test and reading speed for high and low contrast words measured with a sentence generator. The other three studies assessed peripheral vision while subjects fixated through the central portion of the lens. Peripheral contrast sensitivity was measured using two cycles per degree drifting Gabor stimuli. Peripheral motion perception was further evaluated using random dot stimuli. Finally, attention was measured using an established test of useful field of view with three levels of complexity.

resultsThe periphery of the HAL lens significantly reduced low contrast visual acuity, but not high contrast visual acuity, while the effect of the SAL lens was not significant for either. Neither test lens affected reading speed for high contrast words, but the HAL lens significantly affected performance for low contrast words. Neither test lens affected peripheral motion perception or useful field of view.

conclusionsLow contrast visual acuity and reading was slightly reduced while high contrast visual acuity was unaffected when fixating through the periphery of the novel lens designs. None of the peripheral measures of vision was affected by the novel lens designs.

Indexed as

EyeglassesMyopiaAdultChildContrast SensitivityHumansVision, OcularVisual Acuitychildrencontrast sensitivitymotion perceptionmyopiamyopia controlvisual acuity

Identifiers

PMID34529275
PMCPMC9291741

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.