Evidence map›Paper›PMID 34529074›Full record

ReviewThe Plant cell2022

Fifteen compelling open questions in plant cell biology.

Adrienne H K Roeder, Marisa S Otegui, Ram Dixit, Charles T Anderson, Christine Faulkner, Yan Zhang, Maria J Harrison, Charlotte Kirchhelle, Gohta Goshima, Jeremy E Coate and 8 more

Abstract readReview
In one paragraph

Review in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Understanding and optimizing plant growth in water-limited environments: 'growth versus defence' or 'growth versus risk mitigation'?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. What Is a Plant Cell Type in the Age of Single-Cell Biology? It's Complicated.Annual review of cell and developmental biology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Adrienne H K RoederWeill Institute for Cell and Molecular Biology and School of Integrative Plant Science, Section of Plant Biology, Cornell University, Ithaca, New York 14853, USA.ORCID 0000-0001-6685-2984
Marisa S OteguiDepartment of Botany and Center for Quantitative Cell Imaging, University of Wisconsin-Madison, Wisconsin 53706, USA.ORCID 0000-0003-4699-6950
Ram DixitDepartment of Biology and Center for Engineering Mechanobiology, Washington University in St Louis, Missouri 63130, USA.ORCID 0000-0001-7881-2859
Charles T AndersonDepartment of Biology and Center for Lignocellulose Structure and Formation, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0001-7481-3571
Christine FaulknerCrop Genetics, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0003-3905-8077
Yan ZhangState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an, China.ORCID 0000-0002-3501-5857
Maria J HarrisonBoyce Thompson Institute, Ithaca, New York 14853, USA.ORCID 0000-0001-8716-1875
Charlotte KirchhelleDepartment of Plant Sciences, University of Oxford, Oxford OX1 3RB, UK.ORCID 0000-0001-8448-6906
Gohta GoshimaSugashima Marine Biological Laboratory, Graduate School of Science, Nagoya University, Nagoya, Japan.ORCID 0000-0001-7524-8770
Jeremy E CoateDepartment of Biology, Reed College, Portland, Oregon 97202, USA.ORCID 0000-0002-1619-8643
Jeff J DoyleSchool of Integrative Plant Science, Section of Plant Biology and Section of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA.ORCID 0000-0003-1579-9380
Olivier HamantLaboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNR S, Lyon Cedex 07, France.ORCID 0000-0001-6906-6620
Keiko SugimotoCenter for Sustainable Resource Science, RIKEN, Kanagawa 230-0045, Japan.ORCID 0000-0002-9209-8230
Liam DolanGregor Mendel Institute of Molecular Plant Biology GmbH, Vienna 1030, Austria.ORCID 0000-0003-1206-7096
Heather MeyerDepartment of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA.ORCID 0000-0002-9991-6312
David W EhrhardtDepartment of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA.ORCID 0000-0001-6522-7722
Arezki BoudaoudLadHyX, CNRS, Ecole Polytechnique, Institut Polytechnique de Pari s, Palaiseau Cedex 91128 France.ORCID 0000-0002-2780-4717
Carlos MessinaCorteva Agriscience, Johnston, Iowa 50310, USA.ORCID 0000-0002-5501-9281

Funding

Mechanisms for building and remodeling microtubule arraysR35GM139552 · NIGMS · WASHINGTON UNIVERSITY · PI DIXIT, RAMANAND · 2021 to 2025
$2.2M
Mechanisms of robustness in organogenesis (Equipment Supplement 2023)R01GM134037 · NIGMS · CORNELL UNIVERSITY · PI ROEDER, ADRIENNE H · 2020 to 2023
$1.5M
Biotechnology and Biological Sciences Research Council BB/P01979X/1NIGMS NIH HHS R01 GM134037NIGMS NIH HHS R35 GM139552
6 · The paper itself

Abstract

As scientists, we are at least as excited about the open questions-the things we do not know-as the discoveries. Here, we asked 15 experts to describe the most compelling open questions in plant cell biology. These are their questions: How are organelle identity, domains, and boundaries maintained under the continuous flux of vesicle trafficking and membrane remodeling? Is the plant cortical microtubule cytoskeleton a mechanosensory apparatus? How are the cellular pathways of cell wall synthesis, assembly, modification, and integrity sensing linked in plants? Why do plasmodesmata open and close? Is there retrograde signaling from vacuoles to the nucleus? How do root cells accommodate fungal endosymbionts? What is the role of cell edges in plant morphogenesis? How is the cell division site determined? What are the emergent effects of polyploidy on the biology of the cell, and how are any such "rules" conditioned by cell type? Can mechanical forces trigger new cell fates in plants? How does a single differentiated somatic cell reprogram and gain pluripotency? How does polarity develop de-novo in isolated plant cells? What is the spectrum of cellular functions for membraneless organelles and intrinsically disordered proteins? How do plants deal with internal noise? How does order emerge in cells and propagate to organs and organisms from complex dynamical processes? We hope you find the discussions of these questions thought provoking and inspiring.

Indexed as

Plant Physiological PhenomenaCell BiologyPlant CellsPlant Development

Identifiers

PMID34529074
PMCPMC8774073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.