Evidence map›Paper›PMID 34528664›Full record

ArticleGigaScience2021

ISA API: An open platform for interoperable life science experimental metadata.

David Johnson, Dominique Batista, Keeva Cochrane, Robert P Davey, Anthony Etuk, Alejandra Gonzalez-Beltran, Kenneth Haug, Massimiliano Izzo, Martin Larralde, Thomas N Lawson and 11 more

Abstract read
In one paragraph

Article in GigaScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

David JohnsonOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0002-2323-6847
Dominique BatistaOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0002-9563-4991
Keeva CochraneEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0001-7961-0474
Robert P DaveyEarlham Institute, Data infrastructure and algorithms, Norwich Research Park, Norwich NR4 7UZ, UK.ORCID 0000-0002-5589-7754
Anthony EtukEarlham Institute, Data infrastructure and algorithms, Norwich Research Park, Norwich NR4 7UZ, UK.ORCID 0000-0001-8320-660X
Alejandra Gonzalez-BeltranOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0003-3499-8262
Kenneth HaugEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0003-3168-4145
Massimiliano IzzoOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0002-8100-6142
Martin LarraldeStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstraße 1, 69117 Heidelberg, Germany.ORCID 0000-0002-3947-4444
Thomas N LawsonSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.ORCID 0000-0002-5915-7980
Alice MinottoEarlham Institute, Data infrastructure and algorithms, Norwich Research Park, Norwich NR4 7UZ, UK.ORCID 0000-0002-1670-1675
Pablo MorenoEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0002-9856-1679
Venkata Chandrasekhar NainalaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0002-2564-3243
Claire O'DonovanEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0001-8051-7429
Luca PiredduDistributed Computing Group, CRS4: Center for Advanced Studies, Research & Development in Sardinia, Pula 09050, Italy.ORCID 0000-0002-4663-5613
Pierrick RogerCEA, LIST, Laboratory for Data Analysis and Systems' Intelligence, MetaboHUB, Gif-Sur-Yvette F-91191, France.ORCID 0000-0001-8177-4873
Felix ShawEarlham Institute, Data infrastructure and algorithms, Norwich Research Park, Norwich NR4 7UZ, UK.ORCID 0000-0001-9649-5906
Christoph SteinbeckCheminformatics and Computational Metabolomics, Institute for Analytical Chemistry, Lessingstr. 8, 07743 Jena, Germany.ORCID 0000-0001-6966-0814
Ralf J M WeberSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.ORCID 0000-0002-8796-4771
Susanna-Assunta SansoneOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0001-5306-5690
Philippe Rocca-SerraOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford, OX1 3QG, UK.ORCID 0000-0001-9853-5668

Funding

Biotechnology and Biological Sciences Research Council BB/I000771/1Biotechnology and Biological Sciences Research Council BB/J020265/1Biotechnology and Biological Sciences Research Council BB/L021390/1Biotechnology and Biological Sciences Research Council BB/L024055/1Biotechnology and Biological Sciences Research Council BB/L024071/1Biotechnology and Biological Sciences Research Council BB/L024101/1Biotechnology and Biological Sciences Research Council BB/M027635/1Biotechnology and Biological Sciences Research Council BBS/E/T/000PR9817Medical Research Council MR/M009157/1Wellcome TrustWellcome Trust 208381/A/17/ZUK
6 · The paper itself

Abstract

backgroundThe Investigation/Study/Assay (ISA) Metadata Framework is an established and widely used set of open source community specifications and software tools for enabling discovery, exchange, and publication of metadata from experiments in the life sciences. The original ISA software suite provided a set of user-facing Java tools for creating and manipulating the information structured in ISA-Tab-a now widely used tabular format. To make the ISA framework more accessible to machines and enable programmatic manipulation of experiment metadata, the JSON serialization ISA-JSON was developed.

resultsIn this work, we present the ISA API, a Python library for the creation, editing, parsing, and validating of ISA-Tab and ISA-JSON formats by using a common data model engineered as Python object classes. We describe the ISA API feature set, early adopters, and its growing user community.

conclusionsThe ISA API provides users with rich programmatic metadata-handling functionality to support automation, a common interface, and an interoperable medium between the 2 ISA formats, as well as with other life science data formats required for depositing data in public databases.

Indexed as

Biological Science DisciplinesMetadataDatabases, FactualSoftwareAPIlife sciencemetadataopen-source softwarereproducibilitystandards

Identifiers

PMID34528664
PMCPMC8444265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.