Evidence map›Paper›PMID 34528404›Full record

ArticleEarly intervention in psychiatry2022

Elevated emotion reactivity and emotion regulation in individuals at clinical high risk for developing psychosis and those diagnosed with a psychotic disorder.

Leah Vines, Miranda Bridgwater, Peter Bachman, Rebecca Hayes, Sabrina Catalano, Maria Jalbrzikowski

Open access · greenAbstract read
In one paragraph

Article in Early intervention in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Leah VinesDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Miranda BridgwaterDepartment of Psychology, University of Maryland, Baltimore, Maryland, USA.ORCID 0000-0002-3812-9382
Peter BachmanDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Rebecca HayesDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sabrina CatalanoDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Maria JalbrzikowskiDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6574-9432
University of Pittsburgh · USUniversity of Maryland, Baltimore · US

Funding

Neurodevelopmental variation of intrinsic functional connectivity and its relationship to psychosis risk and gene expression - SupplementK01MH112774 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JALBRZIKOWSKI, MARIA · 2017 to 2022
$884k
EEG Biomarkers of Psychosis Risk and Adolescent NeurodevelopmentK23MH097040 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BACHMAN, PETER · 2012 to 2016
$771k
NIMH NIH HHS K01 MH112774NIMH NIH HHS K23 MH097040
6 · The paper itself

Abstract

aimsDisrupted affective processes are core features of psychosis; yet emotion reactivity and emotion regulation impairments have not been fully characterized in individuals at clinical high-risk for developing psychosis (CHR) or adolescents diagnosed with a psychotic disorder (AOP). Characterizing these impairments may provide a fuller understanding of factors contributing to psychosis risk and psychosis onset. Using cross-sectional and longitudinal data, we evaluated (1) group-level effects of emotion reactivity and regulation, (2) stability of group-level effects over time and age, (3) relationships between emotion reactivity and regulation, and (4) associations between these measures and psychosocial functioning and clinical symptomatology.

methodsEighty-seven participants (CHR = 32, TD = 42, AOP = 13; 12-25 years, 1-5 visits) completed the Emotion Reactivity Scale, Difficulties in Emotion Regulation Scale, and Emotion Regulation Questionnaire. We assessed psychotic symptoms with the Structured Interview for Prodromal Syndromes and measured real-world functioning with the Global Functioning: Social and Role Scales. We used analysis of variance to assess Aim 1 and linear mixed models to address Aims 2-4.

resultsCHR and AOP endorsed experiencing heightened levels of emotion reactivity and greater difficulty utilizing emotion regulation strategies compared to TD. These impairments were stable across time and adolescent development. Greater levels of emotion reactivity were associated with greater emotion regulation impairments. Greater impairments in emotion regulation were associated with lower social functioning and greater negative symptom severity.

conclusionTherapeutic interventions designed to reduce emotion reactivity and improve one's ability to utilize emotion regulation strategies may be effective in reducing clinical symptomatology and improving real-world functioning in CHR and AOP.

Indexed as

Emotional RegulationPsychotic DisordersAdolescentCross-Sectional StudiesEmotionsHumansProdromal Symptomsaffectivenegative symptomsprodromalschizophrenia-spectrumsocial functioning

Identifiers

PMID34528404
PMCPMC10282844
OpenAlexW3200276881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.