Evidence map›Paper›PMID 34528353›Full record

ArticleEuropean journal of neurology2021

Fewer COVID-19-associated strokes and reduced severity during the second COVID-19 wave: The Madrid Stroke Network.

Blanca Fuentes, María Alonso de Leciñana, Ricardo Rigual, Sebastián García-Madrona, Fernando Díaz-Otero, Clara Aguirre, Patricia Calleja, José A Egido-Herrero, Joaquín Carneado-Ruiz, Gerardo Ruiz-Ares and 14 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in European journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 7 institutions in 1 country.

Blanca FuentesDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.ORCID 0000-0002-0363-862X
María Alonso de LeciñanaDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.ORCID 0000-0002-4302-6580
Ricardo RigualDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.
Sebastián García-MadronaDepartment of Neurology and Stroke Center, University Hospital Ramón y Cajal, Madrid, Spain.
Fernando Díaz-OteroDepartment of Neurology and Stroke Center, University Hospital Gregorio Marañón, Madrid, Spain.
Clara AguirreDepartment of Neurology and Stroke Center, University Hospital La Princesa, Madrid, Spain.
Patricia CallejaDepartment of Neurology, University Hospital 12 de octubre, Madrid, Spain.
José A Egido-HerreroDepartment of Neurology, University Hospital Clinic San Carlos, Madrid, Spain.
Joaquín Carneado-RuizDepartment of Neurology, University Hospital Puerta de Hierro, Madrid, Spain.
Gerardo Ruiz-AresDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.
Jorge Rodríguez-PardoDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.
Ángela Rodríguez-LópezDepartment of Neurology and Stroke Center, University Hospital Gregorio Marañón, Madrid, Spain.
Álvaro Ximénez-CarrilloDepartment of Neurology and Stroke Center, University Hospital La Princesa, Madrid, Spain.
Alicia de FelipeDepartment of Neurology and Stroke Center, University Hospital Ramón y Cajal, Madrid, Spain.
Fernando OstosDepartment of Neurology, University Hospital 12 de octubre, Madrid, Spain.
Guillermo González-OrtegaDepartment of Neurology, University Hospital 12 de octubre, Madrid, Spain.
Patricia SimalDepartment of Neurology, University Hospital Clinic San Carlos, Madrid, Spain.
Carlos I Gómez EscalonillaDepartment of Neurology, University Hospital Clinic San Carlos, Madrid, Spain.
Pablo Gómez-Porro-SánchezDepartment of Neurology, University Hospital Puerta de Hierro, Madrid, Spain.
Borja Cabal-PazDepartment of Neurology, University Hospital Puerta de Hierro, Madrid, Spain.ORCID 0000-0003-3120-3479
Gemma ReigDepartment of Neurology and Stroke Center, University Hospital La Princesa, Madrid, Spain.
Antonio Gil-NúñezDepartment of Neurology and Stroke Center, University Hospital Gregorio Marañón, Madrid, Spain.
Jaime MasjuánDepartment of Neurology and Stroke Center, University Hospital Ramón y Cajal, Madrid, Spain.ORCID 0000-0003-1329-0943
Exuperio Díez TejedorDepartment of Neurology and Stroke Center, La Paz University Hospital, Madrid, Spain.
Hospital Universitario La Paz · ESHospital Clínico San Carlos · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario de La Princesa · ESHospital Universitario Puerta de Hierro Majadahonda · ESHospital Universitario Ramón y Cajal · ESResearch Institute Hospital 12 de Octubre · ES

Funding

INVICTUS-Plus Spanish Network of the Carlos III Health Institute RD16/0019/0005
6 · The paper itself

Abstract

background and purposeThe experience gained during the first COVID-19 wave could have mitigated the negative impact on stroke care in the following waves. Our aims were to analyze the characteristics and outcomes of patients with stroke admitted during the second COVID-19 wave and to evaluate the differences in the stroke care provision compared with the first wave.

methodsThis retrospective multicenter cohort study included consecutive stroke patients admitted to any of the seven hospitals with stroke units (SUs) and endovascular treatment facilities in the Madrid Health Region. The characteristics of the stroke patients with or without a COVID-19 diagnosis were compared and the organizational changes in stroke care between the first wave (25 February to 25 April 2020) and second wave (21 July to 21 November 2020) were analyzed.

resultsA total of 550 and 1191 stroke patients were admitted during the first and second COVID-19 waves, respectively, with an average daily admission rate of nine patients in both waves. During the second wave, there was a decrease in stroke severity (median National Institutes of Health Stroke Scale 5 vs. 6; p = 0.000), in-hospital strokes (3% vs. 8.1%) and in-hospital mortality (9.9% vs. 15.9%). Furthermore, fewer patients experienced concurrent COVID-19 (6.8% vs. 19.1%), and they presented milder COVID-19 and less severe strokes. Fewer hospitals reported a reduction in the number of SU beds or deployment of SU personnel to COVID-19 dedicated wards during the second wave.

conclusionsDuring the second COVID-19 wave, fewer stroke patients were diagnosed with COVID-19, and they had less stroke severity and milder COVID-19.

Indexed as

COVID-19StrokeCohort StudiesCOVID-19 TestingHumansRetrospective StudiesSARS-CoV-2COVID-19intracerebral hemorrhageischaemic strokeorganized stroke careoutcomes

Identifiers

PMID34528353
PMCPMC8653205
OpenAlexW3200289107

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.