Evidence map›Paper›PMID 34528107›Full record

ArticleEuropean radiology2022

The added value of an artificial intelligence system in assisting radiologists on indeterminate BI-RADS 0 mammograms.

Chunyan Yi, Yuxing Tang, Rushan Ouyang, Yanbo Zhang, Zhenjie Cao, Zhicheng Yang, Shibin Wu, Mei Han, Jing Xiao, Peng Chang and 1 more

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Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

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13citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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13 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Chunyan Yi *Department of Radiology, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Yuxing Tang *PAII Inc, Palo Alto, CA, 94306, USA.
Rushan OuyangDepartment of Radiology, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China.
Yanbo ZhangPAII Inc, Palo Alto, CA, 94306, USA.
Zhenjie CaoPAII Inc, Palo Alto, CA, 94306, USA.
Zhicheng YangPAII Inc, Palo Alto, CA, 94306, USA.
Shibin WuPing An Technology, Shenzhen, 518029, Guangdong, China.
Mei HanPAII Inc, Palo Alto, CA, 94306, USA.
Jing XiaoPing An Technology, Shenzhen, 518029, Guangdong, China.
Peng ChangPAII Inc, Palo Alto, CA, 94306, USA. pengchang@gmail.com.ORCID http://orcid.org/0000-0003-3720-1597
Jie MaDepartment of Radiology, Shenzhen People's Hospital, Shenzhen, 518020, Guangdong, China. majie688@hotmail.com.

Funding

science and technology planning project of shenzhen municipality No.JCYJ20180305164740612
6 · The paper itself

Abstract

objectivesTo investigate the value of an artificial intelligence (AI) system in assisting radiologists to improve the assessment accuracy of BI-RADS 0 cases in mammograms.

methodsWe included 34,654 consecutive digital mammography studies, collected between January 2011 and January 2019, among which, 1088 cases from 1010 unique patients with initial BI-RADS 0 assessment who were recalled during 2 years of follow-up were used in this study. Two mid-level radiologists retrospectively re-assessed these BI-RADS 0 cases with the assistance of an AI system developed by us previously. In addition, four entry-level radiologists were split into two groups to cross-read 80 cases with and without the AI. Diagnostic performance was evaluated using the follow-up diagnosis or biopsy results as the reference standard.

resultsOf the 1088 cases, 626 were actually normal (BI-RADS 1 and no recall required). Assisted by the AI system, 351 (56%) and 362 (58%) normal cases were correctly identified by the two mid-level radiologists hence can be avoided for unnecessary follow-ups. However, they would have missed 12 (10 invasive cancers and 2 ductal carcinoma in situ cancers) and 6 (invasive cancers) malignant lesions respectively as a result. These missed lesions were not highly malignant tumors. The inter-rater reliability of entry-level radiologists increased from 0.20 to 0.30 (p < 0.005) by introducing the AI.

conclusionThe AI system can effectively assist mid-level radiologists in reducing unnecessary follow-ups of mammographically indeterminate breast lesions and reducing the benign biopsy rate without missing highly malignant tumors. KEY POINTS: • The artificial intelligence system could assist mid-level radiologists in effectively reducing unnecessary BI-RADS 0 mammogram recalls and the benign biopsy rate without missing highly malignant tumors. • The artificial intelligence system was capable of detecting low suspicion lesions from heterogeneously and extremely dense breasts that radiologists tended to miss. • The use of an artificial intelligence system may improve the inter-rater reliability and sensitivity, and reduce the reading time of entry-level radiologists in assessing potential lesions in BI-RADS 0 mammograms.

Indexed as

Artificial IntelligenceBreast NeoplasmsFemaleHumansMammographyRadiologistsReproducibility of ResultsRetrospective StudiesArtificial intelligenceBreast cancerDiagnosisDigital mammography

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