Evidence map›Paper›PMID 34528021›Full record

ArticleJournal of affective disorders reports2021

Depression over Time in Persons with Stroke: A Network Analysis Approach.

Sameer A Ashaie, Jinyi Hung, Carter J Funkhouser, Stewart A Shankman, Leora R Cherney

Open access · goldAbstract read
In one paragraph

Article in Journal of affective disorders reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Anticipating depression trajectories by measuring plasticity and change through symptom network dynamics.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
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  11. Review
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  13. Exploring the Complexity of Aphasia With Network Analysis.Journal of speech, language, and hearing research : JSLHR · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sameer A AshaieCenter for Aphasia Research and Treatment, Shirley Ryan AbilityLab.
Jinyi HungDepartment of Audiology and Speech Language Pathology, Mackay Medical College, Taipei, Taiwan.
Carter J FunkhouserPsychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University.
Stewart A ShankmanPsychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University.
Leora R CherneyCenter for Aphasia Research and Treatment, Shirley Ryan AbilityLab.
Northwestern University · USMackay Medical College · TW

Funding

Social Processing Deficits in Remitted Adolescent DepressionR01MH119771 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI AUERBACH, RANDY PATRICK, SHANKMAN, STEWART AARON · 2020 to 2025
$3.7M
ACL HHS 90SFGE0014NIMH NIH HHS R01 MH119771
6 · The paper itself

Abstract

backgroundNetwork analysis has been used to elucidate the relationships among depressive symptoms, but this approach has not been typically used in persons with stroke.

methodUsing a sample of 835 persons with stroke from Stroke Recovery in Underserved Populations 2005-2006 dataset, this study used network analysis to (1) examine changes in relationships between depressive symptoms over time, and (2) test whether baseline network characteristics were prognostic for depression persistence. Network analysis was performed on depressive symptoms collected at discharge from inpatient rehabilitation and at 3-months and 12-months post-discharge.

resultsThe depressive symptom network at discharge was less connected than at both post-discharge follow-ups. Trouble focusing and feeling good as others were the most predictable symptoms at post-discharge, even though they were less connected to other depressive symptoms. Among participants with elevated baseline depression severity, those whose depression persisted 12 months later had more strongly connected networks at discharge than those who recovered 12 months later. LIMITATIONS: This study was unable to determine the directionality of edges. The depression scale was administered differently across time points.

conclusionThese results suggest that baseline network connectivity can predict the course of post-stroke depression, similar to non-stroke populations. More broadly, the study highlights the importance of examining relationships between individual depressive symptoms rather than only sum-scores.

Indexed as

depressionemotionnetwork-analysisstroke

Identifiers

PMID34528021
PMCPMC8438599
OpenAlexW3138574967

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.