Evidence map›Paper›PMID 34527981›Full record

ArticleThe Lancet regional health. Western Pacific2021

Associations between lung function and future cardiovascular morbidity and overall mortality in a predominantly First Nations population: a cohort study.

Andrew J Collaro, Anne B Chang, Julie M Marchant, Mark D Chatfield, Annette Dent, Tamara Blake, Patsi Mawn, Kwun Fong, Margaret S McElrea

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  5. The impact of child and adolescent health on adult respiratory health: the evidence, gaps and priorities.European respiratory review : an official journal of the European Respiratory Society · 2025
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  10. Social determinants of respiratory health from birth: still of concern in the 21st century?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  11. Article
  12. Rapid FEVJournal of Korean medical science · 2023
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Andrew J CollaroAustralian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Anne B ChangAustralian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Julie M MarchantAustralian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Mark D ChatfieldChild Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Annette DentIndigenous Respiratory Outreach Care, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Tamara BlakeDepartment of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Patsi MawnIndigenous Respiratory Outreach Care, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Kwun FongIndigenous Respiratory Outreach Care, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Margaret S McElreaAustralian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Queensland University of Technology · AUThe University of Queensland · AUPrince Charles Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpirometric lung function impairment is an independent predictor of respiratory and cardiovascular disease, and mortality across a broad range of socioeconomic backgrounds and environmental settings. No contemporary studies have explored these relationships in a predominantly regional/remote First Nations population, whose health outcomes are worse than for non-First Nations populations, and First Nations people living in urban centres.

methodsThis was a retrospective cohort study of 1,734 adults (1,113 First Nations) referred to specialist respiratory outreach clinics in the state of Queensland, Australia from February 2012 to March 2020. Regression modelling was used to test associations between lung function and mortality and cardiovascular disease.

findingsAt the time of analysis (August 2020), 189 patients had died: 88 (47%) from respiratory causes and 38 (20%) from cardiovascular causes. When compared to patients with forced expiratory volume in one second (FEV

interpretationReduced lung function even within the clinically normal range is associated with increased mortality, and cardiovascular disease in First Nations Australians. These findings highlight the importance of lung function optimisation and inform the need for future investment to improve outcomes in First Nations populations.

fundingNone.

Indexed as

Cardiovascular DiseaseFirst Nationslung functionOutcomesRespiratory Medicinespirometry

Identifiers

PMID34527981
PMCPMC8403916
OpenAlexW3177524857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.