Evidence map›Paper›PMID 34527810›Full record

ArticleTrauma surgery & acute care open2021

Delays in emergency department intervention for patients with traumatic brain injury in Uganda.

Amber Mehmood, Armaan Ahmed Rowther, Olive Kobusingye, Hussein Ssenyonjo, Nukhba Zia, Adnan A Hyder

Registry-linked trialAbstract read
In one paragraph

Article in Trauma surgery & acute care open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06732752 (Prospective Validation of the New Trauma Score), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06732752 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Prospective Validation of the New Trauma Score (NTS) for Superior Prediction of Mortality Compared to the Revised Trauma Score

TypeobservationalSponsorAl-Nahrain UniversityRan2025 to 2025Enrolled177ConditionsTrauma
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amber MehmoodCollege of Public Health, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-8417-1282
Armaan Ahmed RowtherDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Olive KobusingyeTrauma, Injury, & Disability Unit, Makerere University's School of Public Health, Kampala, Uganda.ORCID 0000-0003-2413-599X
Hussein SsenyonjoNeurosurgery, Mulago National Referral Hospital, Kampala, Uganda.
Nukhba ZiaInternational Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Adnan A HyderDepartment of Global Health, George Washington University Milken Institute School of Public Health, Washington, DC, USA.

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
Traumatic Brain Injury Across the Lifespan in Uganda Research InitiativeR21NS085094 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HYDER, ADNAN A, STEVENS, KENT A · 2015 to 2016
$377k
NIGMS NIH HHS T32 GM136577NINDS NIH HHS R21 NS085094
6 · The paper itself

Abstract

backgroundIn Sub-Saharan African countries, the incidence of traumatic brain injury (TBI) is estimated to be many folds higher than the global average and outcome is hugely impacted by access to healthcare services and quality of care. We conducted an analysis of the TBI registry data to determine the disparities and delays in treatment for patients presenting at a tertiary care hospital in Uganda and to identify factors predictive of delayed treatment initiation.

methodsThe study was conducted at the Mulago National Referral Hospital, Kampala. The study included all patients presenting to the emergency department (ED) with suspected or documented TBI. Early treatment was defined as first intervention within 4 hours of ED presentation-a cut-off determined using sensitivity analysis to injury severity. Descriptive statistics were generated and Pearson's χ

resultsOf 3944 patients, only 4.6% (n=182) received an intervention for TBI management within 1 hour of ED presentation, whereas 17.4% of patients (n=708) received some treatment within 4 hours of presentation. 19% of those with one or more serious injuries and 18% of those with moderate to severe head injury received care within 4 hours of arrival. Factors independently associated with early treatment included young age, severe head injury, and no known pre-existing conditions, whereas older or female patients had significantly less odds of receiving early treatment. DISCUSSION: With the increasing number of patients with TBI, ensuring early and appropriate management must be a priority for Ugandan hospitals. Delay in initiation of treatment may impact survival and functional outcome. Gender-related and age-related disparities in care should receive attention and targeted interventions. LEVEL OF EVIDENCE: Prognostic and epidemiological study; level II evidence.

Indexed as

brain injurieshealth care disparitiesoutcomesquality of caretraumatic

Identifiers

PMID34527810
PMCPMC8395360

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.