Evidence map›Paper›PMID 34527765›Full record

ArticleGlobal pediatric health2021

Cardiac Complications Caused by Respiratory Syncytial Virus Infection: Questionnaire Survey and a Literature Review.

Hisashi Kawashima, Natsuko Inagaki, Toshihiro Nakayama, Shinichiro Morichi, Shigeo Nishimata, Gaku Yamanaka, Yasuyo Kashiwagi

Open access · goldAbstract read
In one paragraph

Article in Global pediatric health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. The risk of cardiac disease events after respiratory syncytial virus disease: a systematic literature review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Viral Myocarditis-From Pathophysiology to Treatment.Journal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hisashi KawashimaDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.ORCID https://orcid.org/0000-0003-2571-9962
Natsuko InagakiDepartment of Clinical Genetic Center, Tokyo Medical University, Shinjuku-ku, Tokyo Japan.
Toshihiro NakayamaDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.
Shinichiro MorichiDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.
Shigeo NishimataDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.
Gaku YamanakaDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.
Yasuyo KashiwagiDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Shinjuku-ku, Japan.
Tokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated 22 cases of patients with myocarditis during respiratory syncytial virus (RSV) infection by a questionnaire survey, and performed a literature search to clarify their characteristics. The age distribution was divided into 2 groups, that is, 1 group comprised of patients younger than 4-years old and the other comprised patients older than 15 years. ECG demonstrated disturbance of the conduction system (AV block) in 7 out of 18 patients (38.8%), myocardial damage (ST-T change) in 9 out of 18 patients (50.0%), and tachycardia in 3 out of 18 patients (16.6%). Echocardiography displayed a robust decrease in left-heart function in 12 out of 14 patients. The outcome was 2 deaths, 1 pacemaker placement, 4 patients with mild sequel. Our data suggest that RSV myocarditis caused by RSV infection can be divided into 3 different pathophysiologies, characterized by disturbance of the conduction system, myocardial damage, and increase of autonomy.

Indexed as

AV blockmyocardial damageNT-pro BNPSIDStachycardia

Identifiers

PMID34527765
PMCPMC8436282
OpenAlexW3197354426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.