ArticleGland surgery2021
A nomogram for predicting overall-specific survival in thyroid cancer patients with total thyroidectomy: a SEER database analysis.
Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Accuracy of papillary thyroid cancer prognostic nomograms: a systematic review.Endocrine connections · 2023Article
- An ultrasound model for predicting recurrence of papillary thyroid carcinoma after complete endoscopic resection.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA good predictive model requires patients to attend consultations for prognosis and subsequent clinical follow up. The aim of the present study was to build a nomogram chart with independent prognostic factors for thyroid cancer (TC) patients with total thyroidectomy.
methodsThis was a retrospective, observational study. Data were collected from the Surveillance, Epidemiology, End Results (SEER) database and approved by the institutional review board of our institution. In total, 11,614 patients with TC after thyroidectomy were selected from 2010 to 2015. We divided the selected patients into a modeling group and a verification group at a ratio of 7:3. The effective factors were selected to establish the nomogram model through Cox analysis. Finally, internal verification was carried out through the testing group.
resultsChi-squared analysis of various factors in the modeling group and the testing group had no significant statistical significance, indicating that random grouping was meaningful. Most of the TC patients were female patients. The following variables were selected through univariate and multivariate Cox analysis for overall-specific survival: age, histological type, grade, tumor size, stage TMN, and sex. These variables were used to establish predictions of 3- and 5-year survival rates using a nomogram. Both the modeling group and the verification group had good predictive ability with their C-index all greater than 0.8.
conclusionsWe established the first postoperative prediction model of TC with total thyroidectomy through the variables selected via the Cox multivariate analysis, which laid the foundation for the prognostic prediction and postoperative follow up of each patient.
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