Evidence map›Paper›PMID 34527482›Full record

ReviewCureus2021

Acute Anemia and Myocardial Infarction.

Jaskamal Padda, Khizer Khalid, Gazala Hitawala, Nitya Batra, Sindhu Pokhriyal, Ayushi Mohan, Ayden Charlene Cooper, Gutteridge Jean-Charles

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. The Negative Influence and Adverse Outcome of Red Blood Cell Transfusion in Contemporary Percutaneous Coronary Interventions.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Postoperative anemia in cardiac surgery patients: a narrative review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Review
  13. Long-Term Exposure to Ambient PMJournal of the American Heart Association · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jaskamal PaddaInternal Medicine, JC Medical Center, Orlando, USA.
Khizer KhalidInternal Medicine, JC Medical Center, Orlando, USA.
Gazala HitawalaInternal Medicine, JC Medical Center, Orlando, USA.
Nitya BatraInternal Medicine, JC Medical Center, Orlando, USA.
Sindhu PokhriyalInternal Medicine, JC Medical Center, Orlando, USA.
Ayushi MohanInternal Medicine, JC Medical Center, Orlando, USA.
Ayden Charlene CooperInternal Medicine, JC Medical Center, Orlando, USA.
Gutteridge Jean-CharlesInternal Medicine, JC Medical Center, Orlando, USA.
Avalon University School of Medicine · CWOrlando Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various studies have established the prognosis of anemia in myocardial infarction (MI). Both chronic and acute anemia lead to poor outcomes in MI. Regardless, the association of anemia with MI and its management varies. In this study, the literature was analyzed to determine the association between acute anemia and MI based on the pathophysiology, outcomes, and management options. Acute anemia results in decreased blood supply and sudden hypoxia to the heart. Additionally, it exacerbates the preexisting compromised coronary blood supply in patients with MI. Thus, there is a disproportionate oxygen supply and demand ratio to the heart. It was found that anemia increases all-cause mortality in acute MI. However, it is unclear whether anemia is the direct contributor to mortality in these patients. For the management of MI, percutaneous coronary intervention (PCI) is commonly used. Increased incidence of hospital-acquired anemia (HAA) is reported in patients after PCI. However, the cause of HAA in these patients is not well established. Antiplatelet therapy in these patients is also considered to be the culprit for HAA. Nonetheless, no clear evidence is available. There is no consensus or criteria for the treatment of acute anemia in MI patients. Researchers have explored management options such as blood transfusion, erythropoietin-stimulating agent, and iron therapy. Further studies are warranted for a better understanding and management of MI in patients with anemia and vice versa.

Indexed as

anemia and mianemia and pciepidemiology of anemiapathophysiology of anemia in mitreatment of anemia in mi

Identifiers

PMID34527482
PMCPMC8432420
OpenAlexW3189744773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.