Evidence map›Paper›PMID 34527475›Full record

ArticleCureus2021

Management of Pediatric Strokes With Alteplase (Tissue Plasminogen Activator).

Asia Filatov, Jaime Alvarez, Jessica Seibert, Marc Swerdloff

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asia FilatovNeurology, Florida Atlantic University, Boca Raton, USA.
Jaime AlvarezEmergency Medicine, Boca Raton Regional Hospital, Boca Raton, USA.
Jessica SeibertNeurology, Boca Raton Regional Hospital, Boca Raton, USA.
Marc SwerdloffNeurology, Marcus Neuroscience Institute, Boca Raton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the pediatric population, ischemic stroke is rare. Pediatric patients with acute ischemic stroke are eligible for intravenous thrombolysis and/or mechanical thrombectomy. However, due to the rare occurrence of strokes and national shortage of pediatric neurologists, timely diagnosis and appropriate treatment can be challenging. We report a case of a 16-year-old female who presented with an acute ischemic stroke to our adult comprehensive stroke program.

Indexed as

alteplasepediatric strokestroketissue plasminogen activator (tpa)tpa

Identifiers

PMID34527475
PMCPMC8431982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.