ArticleJournal of thoracic disease2021
Conventional open versus hybrid aortic arch repair: a meta-analysis of propensity-matched studies.
Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Clinical outcomes of hybrid surgery in the treatment of aortic arch disease: a retrospective study.Journal of thoracic disease · 2026Article
- Open, Hybrid and Endovascular Management of Aortic Arch Aneurysms: Recent Updates and Future Directions.Journal of clinical medicine · 2026Review
- Neurological complications post aortic arch surgery: a state of art review.Journal of cardiothoracic surgery · 2025Review
- Early and 3-Year Outcomes of Frozen Elephant Trunk Procedure with Evolving E-vita Hybrid Grafts: A Retrospective Single-Centre Cohort Study over 11 Years.Journal of cardiovascular development and disease · 2025Article
- Hybrid and Endovascular Management of Aortic Arch Pathology.Journal of clinical medicine · 2024Review
- Physician-modified endograft for symptomatic zone 2 penetrating ulcer of the aortic arch without bridging stenting of the left subclavian artery for vertebral preservation.Journal of vascular surgery cases and innovative techniques · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComparison of conventional (open) surgical versus hybrid aortic arch repair remains debatable. While the majority of previous comparative studies including meta-analyses contained primarily risk-unadjusted cohorts, those focusing on propensity-matched comparisons were limited by their small sample size. We aimed to compare outcomes of these two approaches through an up-to-date search and meta-analysis of the best evidence currently available in the literature.
methodsThe PubMed/MEDLINE, EMBASE, and Cochrane library from inception to September 2019 were searched to identify articles reporting propensity-score matching data on open versus hybrid aortic arch repair. Patients' baseline characteristics and clinical outcomes were extracted from the articles and pooled for analysis. Heterogeneity and biases were assessed among the included studies.
resultsFive studies, including a total of 378 patients (189 pairs), were included in the study. The two groups were similar in patients' baseline characteristics. Stroke rate favoured the open group [2.1% versus 14.3%, OR 0.18 (0.07, 0.46), P=0.0004, I
conclusionsOpen and hybrid repairs do not offer equivalent outcomes. Compared with hybrid aortic arch repair, conventional surgical aortic repair could be associated with favourable outcomes including postoperative stroke. Hybrid repair does not appear to provide better survival. Operative approaches should be carefully selected in treating aortic arch pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.