Evidence map›Paper›PMID 34527299›Full record

ArticleJournal of clinical and translational science2021

Encouraging the scale-up of proven interventions: Infrastructure development for the "Evidence-to-Implementation" award.

Andrew Quanbeck, Roberta A Johnson, Mondira Saha-Muldowney, Felice Resnik, Sheena Hirschfield, Rachael R Meline, Jane E Mahoney

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew QuanbeckD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.ORCID https://orcid.org/0000-0003-0762-4804
Roberta A JohnsonDepartment of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.
Mondira Saha-MuldowneyD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.
Felice ResnikD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.
Sheena HirschfieldD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.
Rachael R MelineD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.
Jane E MahoneyD & I (Dissemination and Implementation) Launchpad, Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, USA.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
NCATS NIH HHS UL1 TR002373
6 · The paper itself

Abstract

BACKGROUND/

objectiveAlthough most research universities offer investigators help in obtaining patents for inventions, investigators generally have few resources for scaling up non-patentable innovations, such as health behavior change interventions. In 2017, the dissemination and implementation (D & I) team at the University of Wisconsin's Clinical and Translational Science Award (CTSA) created the Evidence-to-Implementation (E2I) award to encourage the scale-up of proven, non-patentable health interventions. The award was intended to give investigators financial support and business expertise to prepare evidence-based interventions for scale-up.

methodsThe D & I team adapted a set of criteria named Critical Factors Assessment, which has proven effective in predicting the success of entrepreneurial ventures outside the health care environment, to use as review criteria for the program. In March 2018 and February 2020, multidisciplinary panels assessed proposals using a review process loosely based on the one used by the NIH for grant proposals, replacing the traditional NIH scoring criteria with the eight predictive factors included in Critical Factors Assessment.

resultstwo applications in 2018 and three applications in 2020 earned awards. Funding has ended for the first two awardees, and both innovations have advanced successfully.

conclusionLate-stage translation, though often overlooked by the academic community, is essential to maximizing the overall impact of the science generated by CTSAs. The Evidence-to-implementation award provides a working model for supporting late-stage translation within a CTSA environment.

Indexed as

commercializationentrepreneurismImplementationlate-stage translationnon-patentable interventions

Identifiers

PMID34527299
PMCPMC8427544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.