Evidence map›Paper›PMID 34527256›Full record

ArticleOxford medical case reports2021

Early HER2-positive breast cancer arising from a fibroadenoma: a case report.

Akihiro Fujimoto, Kazuo Matsuura, Tomonori Kawasaki, Yuki Ichinose, Asami Nukui, Miyuki Hiratsuka, Aya Asano, Hiroko Shimada, Akihiko Osaki, Toshiaki Saeki

Open access · goldAbstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Akihiro FujimotoBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Kazuo MatsuuraBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Tomonori KawasakiDepartment of Pathology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Yuki IchinoseBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Asami NukuiBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Miyuki HiratsukaBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Aya AsanoBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Hiroko ShimadaBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Akihiko OsakiBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Toshiaki SaekiBreast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Saitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer arising from fibroadenoma (FA) is rare, in which almost all reported cases are human epidermal growth factor receptor 2 (HER2)-negative. This is the first report to describe a case of HER2-positive breast cancer arising from FA that was treated with chemotherapy plus anti-HER2 therapy. In this early case, upfront surgery outcomes guided the selection of appropriate systemic therapy. A 31-year-old woman previously diagnosed with FA experienced tumor growth. Core needle biopsy and imaging studies confirmed a diagnosis of stage IIA HER2-positive invasive ductal carcinoma (IDC) with no evidence of lymph node metastasis (cT2N0M0). Breast-conserving surgery was performed. Pathological diagnosis revealed stage IA IDC with a predominant intraductal component (pT1aN0M0), arising from FA. In conclusion, we encountered an extremely rare case of HER2-positive breast cancer arising from FA in which pathological infiltration was difficult to predict based on preoperative imaging.

Identifiers

PMID34527256
PMCPMC8436269
OpenAlexW3201144966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.