Evidence map›Paper›PMID 34527173›Full record

ArticleOxidative medicine and cellular longevity2021

Xutao Zhang, Chunxiu Zhou, Lingchao Miao, Yi Tan, Yan Zhou, Meng Sam Cheong, Yu Huang, Yitao Wang, Hua Yu, Wai San Cheang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Efficacy and safety ofFrontiers in pharmacology · 2024
    Pooled it
  2. Food science & nutrition · 2026
    Article
  3. SteamedNutrients · 2025
    Article
  4. Review
  5. Article
  6. Nutrients · 2024
    Review
  7. Review
  8. Review
  9. Plants (Basel, Switzerland) · 2022
    Article
  10. 3,4',5-Trimethoxy-Antioxidants (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Xutao Zhang *State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Chunxiu Zhou *State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Lingchao MiaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Yi TanState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Yan ZhouState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Meng Sam CheongState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Yu HuangSchool of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Yitao WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.ORCID https://orcid.org/0000-0003-4355-6490
Hua YuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Wai San CheangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.ORCID https://orcid.org/0000-0002-1152-7997
University of Macau · MOChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies revealed a cardioprotective potential of

Indexed as

AMP-Activated Protein KinasesAnimalsAortaDiet, High-FatEndoplasmic Reticulum StressEthanolHumansHuman Umbilical Vein Endothelial CellsMaleMiceMice, Inbred C57BLNitric Oxide Synthase Type IIIObesityOxidative StressPanax notoginsengPhosphorylationAMP-Activated Protein KinasesEthanolNitric Oxide Synthase Type IIIPlant ExtractsReactive Oxygen SpeciesSaponins

Identifiers

PMID34527173
PMCPMC8437594
OpenAlexW3196758316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.