Evidence map›Paper›PMID 34527158›Full record

ArticleThe Pan African medical journal2021

High prevalence of uncontrolled hypertension among patients with type 2 diabetes mellitus: a hospital-based cross-sectional study in Southwestern Uganda.

Patrick Kambale Saasita, Siraj Senoga, Kakule Muhongya, David Collins Agaba, Richard Migisha

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patrick Kambale SaasitaDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Siraj SenogaDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Kakule MuhongyaDepartment of Accident and Emergency, Kampala International University Western campus, Ishaka, Bushenyi, Uganda.
David Collins AgabaDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Richard MigishaDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Mbarara University of Science and Technology · UGKampala International University · UG

Funding

Mbarara University Research Training Initiative (MURTI)D43TW010128 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OBUA, CELESTINO · 2015 to 2019
$3.5M
FIC NIH HHS D43 TW010128
6 · The paper itself

Abstract

introductionmost patients with diabetes mellitus are prone to uncontrolled blood pressures despite effective medical therapies; only about 30% of hypertensive patients have their blood pressures controlled. Poor control of hypertension is associated with increased risk for cardiovascular mortality and morbidity. We aimed to determine the prevalence and associated factors of uncontrolled hypertension among patients with type 2 diabetes mellitus (T2DM) attending ambulatory care at Mbarara Regional Referral Hospital, Southwestern Uganda.

methodswe conducted a cross-sectional study from January to April 2019, among hypertensive T2DM patients. We used a structured questionnaire to obtain data on socio-demographic and clinical characteristics. We defined uncontrolled hypertension in participants with blood pressure ≥140/90mmHg and performed binary logistic regression to determine factors associated with uncontrolled hypertension.

resultswe analyzed data of 206 hypertensive participants with concomitant T2DM, with a median age of 54 (IQR, 49-60) years, and median duration of diabetes of 4 (IQR, 3-8) years; 71% were female. The prevalence of uncontrolled hypertension was 82.5% (170/206). Isolated systolic hypertension (aOR=7.58; 95%CI: 2.18-26.36, P=0.001) and left ventricular hypertrophy (LVH) (aOR=5.38; 95%CI: 1.11-26.10, P=0.037) were significantly associated with uncontrolled hypertension.

conclusionthis study revealed a high prevalence of uncontrolled hypertension among T2DM patients in Southwestern Uganda. Isolated systolic hypertension and LVH were the key factors associated with uncontrolled hypertension. We recommend optimization therapy to reduce the burden of uncontrolled hypertension among patients with T2DM especially in those with isolated systolic hypertension, and left ventricular hypertrophy, who are at higher cardiovascular risk.

Indexed as

AdolescentAdultAgedAmbulatory CareCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesUgandadiabetesprevalenceUgandaUncontrolled hypertension

Identifiers

PMID34527158
PMCPMC8418183
OpenAlexW3174477783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.