Evidence map›Paper›PMID 34527077›Full record

ArticleComputational and mathematical methods in medicine2021

Angelica sinensis Polysaccharide Alleviates Myocardial Fibrosis and Oxidative Stress in the Heart of Hypertensive Rats.

Xiaolong Song, Junhong Kong, Jun Song, Renyou Pan, Lei Wang

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. The Effect of aPharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Pharmacological action ofFrontiers in pharmacology · 2024
    Review
  8. Review
  9. Review
  10. Drugs for treating myocardial fibrosis.Frontiers in pharmacology · 2023
    Review
  11. Plants (Basel, Switzerland) · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaolong SongDepartment of Cardiology, Yancheng Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng, Jiangsu Province, China.ORCID https://orcid.org/0000-0003-2350-2161
Junhong KongDepartment of Treating Disease Center, Changzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Changzhou, Jiangsu Province, China.ORCID https://orcid.org/0000-0002-1921-504X
Jun SongDepartment of Cardiology, Yancheng Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng, Jiangsu Province, China.ORCID https://orcid.org/0000-0002-5234-5567
Renyou PanDepartment of Cardiology, Yancheng Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng, Jiangsu Province, China.ORCID https://orcid.org/0000-0002-4814-2978
Lei WangLaboratory of Morphology, Xuzhou Medical University, Xuzhou, Jiangsu Province, China.ORCID https://orcid.org/0000-0001-8367-1296
Nanjing University of Chinese Medicine · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research is aimed at studying the effect of Angelica sinensis polysaccharide (ASP) extracted from the Lixinshui prescription on cardiac disease induced by hypertension in rats. Rat models of cardiovascular disease were established, and the associated factors were measured. The data showed that ASP treatment increased the ejection fraction and short axis shortening rate, while decreasing the LV end-diastolic diameter, LV end-systolic diameter, LV end-diastolic volume, and LV end-systolic volume in HHD rats. ASP downregulated the expression level of TGF-

Indexed as

PhytotherapyAngelica sinensisAnimalsApoptosisComputational BiologyDisease Models, AnimalDrugs, Chinese HerbalFibrosisHeartHypertensionMaleMyocardiumMyocytes, CardiacOxidative StressPolysaccharidesRatsangelicae sinensis extractDrugs, Chinese HerbalPolysaccharides

Identifiers

PMID34527077
PMCPMC8437656
OpenAlexW3196859772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.