Evidence map›Paper›PMID 34527048›Full record

ArticleInternational journal of endocrinology2021

Morning Serum Cortisol as a Predictor for the HPA Axis Recovery in Cushing's Disease.

Q Cui, D Liu, B Xiang, Q Sun, L Fan, M He, Y Wang, X Zhu, H Ye

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Q CuiDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
D LiuDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
B XiangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
Q SunDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-8446-4480
L FanDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
M HeDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
Y WangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
X ZhuDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
H YeDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-6932-3145
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe suppressed hypothalamic-pituitary-adrenal (HPA) axis after successful surgery for Cushing's disease (CD) will recover in almost all patients. We aimed to identify the predictive factors for HPA axis recovery in CD patients with postoperative remission.

resultsPeak cortisol in LDT was found only to be positively correlative with morning serum cortisol (MSC) (

conclusionsMSC is a viable first-step diagnostic predictor for HPA axis recovery in CD patients with postoperative remission. For the patients with cortisol levels between 4.18 and 10.74

Identifiers

PMID34527048
PMCPMC8437621
OpenAlexW3198412100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.