Evidence map›Paper›PMID 34526996›Full record

ArticleFrontiers in immunology2021

Transcriptional Changes in Regulatory T Cells From Patients With Autoimmune Polyendocrine Syndrome Type 1 Suggest Functional Impairment of Lipid Metabolism and Gut Homing.

Amund Holte Berger, Eirik Bratland, Thea Sjøgren, Marte Heimli, Torgeir Tyssedal, Øyvind Bruserud, Stefan Johansson, Eystein Sverre Husebye, Bergithe Eikeland Oftedal, Anette Susanne Bøe Wolff

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Amund Holte BergerDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Eirik BratlandDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Thea SjøgrenDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Marte HeimliDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Torgeir TyssedalDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Øyvind BruserudDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Stefan JohanssonDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Eystein Sverre HusebyeDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Bergithe Eikeland OftedalDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Anette Susanne Bøe WolffDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Haukeland University Hospital · NOUniversity of Bergen · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune polyendocrine syndrome type I (APS-1) is a monogenic model disorder of organ-specific autoimmunity caused by mutations in the

Indexed as

AdultCase-Control StudiesFatty Acid Synthase, Type IFemaleHumansIntestinal MucosaLipid MetabolismMaleMiddle AgedPolyendocrinopathies, AutoimmuneT-Lymphocytes, RegulatoryFASN protein, humanFatty Acid Synthase, Type IAPS-1autoimmune diseaseautoimmune polyendocrine syndrome type 1flow cytometryRNAseq analysistranscriptomicsTregs (regulatory T cells)

Identifiers

PMID34526996
PMCPMC8435668
OpenAlexW3198652317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.