Evidence map›Paper›PMID 34526825›Full record

ArticleHIV/AIDS (Auckland, N.Z.)2021

Incidence and Predictors of Hypertension Among HIV Patients Receiving ART at Public Health Facilities, Northwest Ethiopia: A One-Year Multicenter Prospective Follow-Up Study.

Henok Mulugeta, Abebe Dilie Afenigus, Dessalegn Haile, Haile Amha, Getachew Mullu Kassa, Muluken Wubetu, Ermias Abebaw, Dube Jara

Open access · goldAbstract read
In one paragraph

Article in HIV/AIDS (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Henok MulugetaDepartment of Nursing, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0001-7330-3609
Abebe Dilie AfenigusDepartment of Nursing, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0003-4213-3664
Dessalegn HaileDepartment of Nursing, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0002-3204-2120
Haile AmhaDepartment of Nursing, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.
Getachew Mullu KassaDepartment of Public Health, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0002-8095-7376
Muluken WubetuDepartment of Pharmacy, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.
Ermias AbebawDepartment of Pediatrics and Child Health, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Dube JaraDepartment of Public Health, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0002-7095-9941
Debre Markos University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe introduction of highly active retroviral therapy has dramatically reduced mortality and improved survival among HIV patients. However, there is a possible risk of comorbid complications such as hypertension. Little evidence is available regarding the incidence of hypertension among HIV patients receiving anti-retroviral therapy in Ethiopia. PURPOSE: To assess the incidence and predictors of hypertension among HIV positive patients receiving ART at Public Health Facilities, Northwest Ethiopia. PATIENTS AND

methodsA one-year prospective follow-up study was conducted among a cohort of 302 new adult individuals initiating on a standard anti-retroviral therapy regimen with a median (IQR) age of 35 years (IQR=30-41). A pretested data extraction checklist was used to extract baseline patient records. The collected data were entered into Epi-Data version 3.1 and exported to STATA version 14 for analysis. The incidence rate was calculated, and a Kaplan-Meier survival curve was used to estimate the survival probabilities of developing hypertension. Cox proportional hazards model was fitted to identify the predictors of hypertension.

resultsAbout 40 (13.25) new hypertensive cases were observed during the follow-up period, and the remaining 262 (86.75%) were censored. The overall incidence rate of hypertension was 16.35 per 1000 person-month with 2447 patient-month observations. Male sex (AHR = 2.45, 95% CI: 1.02, 6.14), old age (AHR = 2.83, 95% CI: 1.08, 7.45), high BMI (AHR = 6.54, 95% CI: 2.03, 21.13), diabetic comorbidity (AHR = 2.36, 95% CI: 1.07, 5.22), and patients who were on Zidovudine (AZT)-based ART regimen (AHR =3.47, 95% CI: 1.10, 10.94) were significant predictors for the development of hypertension.

conclusionThe findings of this study revealed that incident hypertension is a common problem among HIV patients receiving ART. Routine monitoring of blood pressure and screening and treating high blood pressure should be an integral part of follow-up for HIV patients in ART clinics.

Indexed as

anti-retroviral therapyEthiopiaHIV/AIDShypertension

Identifiers

PMID34526825
PMCPMC8435532
OpenAlexW3197271082

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.