Evidence map›Paper›PMID 34526803›Full record

ArticlePharmacogenomics and personalized medicine2021

Gephyrin and

Hamdy N El-Tallawy, Sawsan Abuhamdah, Ahmed Y Nassar, Wafaa M A Farghaly, Tahia H Saleem, Sara A Atta, Ayat A Sayed, Amal M Tohamy, Mohammed H Hassan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Hamdy N El-TallawyDepartment of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Sawsan AbuhamdahDepartment of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
Ahmed Y NassarDepartment of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Wafaa M A FarghalyDepartment of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0001-6094-1994
Tahia H SaleemDepartment of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0001-8575-4714
Sara A AttaDepartment of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Ayat A SayedDepartment of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Amal M TohamyDepartment of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Mohammed H HassanDepartment of Medical Biochemistry, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.ORCID 0000-0003-2698-9438
Assiut University · EGSouth Valley University · EGUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGephyrin ( PATIENTS AND

methodsThis case-control study enrolled 100 patients (group A) and 100 healthy, age and sex-matched controls, unrelated to patients (group B). TaqMan™ assays using real-time PCR were run for genotyping of rs928553T/C and rs12782374G/A in all participants.

results

conclusionMutation of both

Indexed as

pharmacoresistant epilepsyreal time-PCRrs12782374G/Ars928553T/C

Identifiers

PMID34526803
PMCPMC8437390
OpenAlexW3197181352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.