Evidence map›Paper›PMID 34526796›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Consensus on the Use of Hyaluronic Acid Fillers from the Cohesive Polydensified Matrix Range: Best Practice in Specific Facial Indications.

Jani van Loghem, Sonja Sattler, Gabriela Casabona, Sebastian Cotofana, Sabrina Guillen Fabi, Kate Goldie, Uliana Gout, Martina Kerscher, Ting Song Lim, Carla de Sanctis Pecora and 5 more

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Conditions to Consider When Choosing Fillers.Journal of cosmetic dermatology · 2025
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Treatment of the Temples: Brazilian Consensus.Aesthetic plastic surgery · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Effects of hyaluronic acid on skin at the cellular level: a systematic review.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jani van LoghemFalck Clinic, Aesthetic Medicine Centre, Amsterdam, the Netherlands.ORCID 0000-0001-6720-7434
Sonja SattlerRosenpark Clinic, Darmstadt, Germany.
Gabriela CasabonaOcean Clinic, Marbella, Spain.
Sebastian CotofanaAlbany Medical College, Albany, NY, USA.
Sabrina Guillen FabiCosmetic Laser Dermatology and University of California, San Diego, CA, USA.
Kate GoldieEuropean Medical Aesthetics Ltd, London, UK.
Uliana GoutAesthetic Medicine Clinic, London, UK.
Martina KerscherUniversity of Hamburg, Hamburg, Germany.ORCID 0000-0002-4563-5136
Ting Song LimClique Clinic, Kuala Lumpur, Malaysia.ORCID 0000-0001-6637-3836
Carla de Sanctis PecoraDermatologie-Clínica, Cirurgia, Cosmiatria e Laser, São Paulo, Brazil.ORCID 0000-0002-0711-281X
Gerhard SattlerRosenpark Clinic, Darmstadt, Germany.
Ada Trindade de AlmeidaClínica de Dermatologia do Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.
Rungsima WanitphakdeedechaiSKY Innovative Skin & Laser Surgery Center, Bangkok, Thailand.ORCID 0000-0002-3926-2193
Philip WerschlerPremier Clinical Research, Spokane, WA, USA.
Tatjana PavicicPrivate Practice for Dermatology and Aesthetics, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the treatment indications for the Cohesive Polydensified Matrix

methodsAn international panel of experts in the field of aesthetic medicine convened to develop guidelines on effective and safe injection technique when performing treatments with the CPM-HA range of soft-tissue fillers.

resultsConsensus members considered treatment indications in the upper, middle and lower face. Landmark deficiencies and anatomical considerations are described for each indication and consensus recommendations provided on the optimal product, injection depth and treatment technique. This is supplemented by the experts advice on avoidance of complications. Throughout, an evidence-based approach to selection of products and injection techniques is provided. The result is a fully tailored approach to a range of indications covering the full portfolio of CPM-HA products, including the newest addition for skin revitalization.

conclusionThe recommendations in this consensus document are provided to assist clinicians in the selection of CPM-HA products, administration techniques and depths of injection with the aim of providing seamless and natural treatment results, enhanced safety and patient satisfaction.

Indexed as

anatomyBeloterocohesive polydensified matrixconsensushyaluronic acidinjection technique

Identifiers

PMID34526796
PMCPMC8435881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.