Evidence map›Paper›PMID 34526768›Full record

ArticleInternational journal of nanomedicine2021

Chlorambucil-Iron Oxide Nanoparticles as a Drug Delivery System for Leukemia Cancer Cells.

Samer Hasan Hussein-Al-Ali, Mohd Zobir Hussein, Saifullah Bullo, Palanisamy Arulselvan

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Samer Hasan Hussein-Al-AliFaculty of Pharmacy, Isra University, Amman, 11622, Jordan.ORCID 0000-0002-8760-6069
Mohd Zobir HusseinMaterials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Selangor, 43400, Malaysia.ORCID 0000-0002-0741-261X
Saifullah BulloMaterials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Selangor, 43400, Malaysia.
Palanisamy ArulselvanLaboratory of Vaccines and Immunotherapeutic, Institute of Bioscience, Universiti Putra Malyasia, Serdange, Selangor, 43400 UPM, Malaysia.ORCID 0000-0002-1835-9738
Universiti Putra Malaysia · MYIsra University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTraditional cancer therapies may have incomplete eradication of cancer or destroy the normal cells. Nanotechnology solves the demerit by a guide in surgical resection of tumors, targeted chemotherapies, selective to cancerous cells, etc. This new technology can reduce the risk to the patient and automatically increased the probability of survival. Toward this goal, novel iron oxide nanoparticles (IONPs) coupled with leukemia anti-cancer drug were prepared and assessed.

methodsThe IONPs were prepared by the co-precipitation method using Fe

resultsThe as-prepared IONPs were found to be magnetite (Fe

conclusionThis work shows that Chloramb-CS-IONPs nanocomposite is a promising candidate for magnetically targeted drug delivery for leukemia anti-cancer agents.

Indexed as

ChitosanLeukemiaMagnetite NanoparticlesChlorambucilDrug Delivery SystemsHumansMagnetic Iron Oxide NanoparticlesSpectroscopy, Fourier Transform InfraredChitosanChlorambucilMagnetite Nanoparticlesanticancerchlorambucilleukemia cell linesmagnetic nanoparticlessustained release

Identifiers

PMID34526768
PMCPMC8435621
OpenAlexW3197313680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.