ArticleNature2021
Reproducibility: expect less of the scientific paper.
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recommendations for robust and reproducible preclinical research in personalised medicine.BMC medicine · 2023Guideline
- Analytic approaches to clinical validation of results from preclinical models of glioblastoma: A systematic review.PloS one · 2022Pooled it
- The Gifted Outlier in Academic Medicine: Toward a Balanced Framework for Recognizing Diverse Excellence.Cureus · 2025Article
- Review
- For a proper use of frequentist inferential statistics in public health.Global epidemiology · 2024Article
- OBSERVE: guidelines for the refinement of rodent cancer models.Nature protocols · 2024Review
- Memory effects of prior subculture may impact the quality of multiomic perturbation profiles.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Finding the right power balance: Better study design and collaboration can reduce dependence on statistical power.PLoS biology · 2024Article
- From the Catastrophic Objective Irreproducibility of Cancer Research and Unavoidable Failures of Molecular Targeted Therapies to the Sparkling Hope of Supramolecular Targeted Strategies.International journal of molecular sciences · 2023Review
- Automated cell segmentation for reproducibility in bioimage analysis.Synthetic biology (Oxford, England) · 2023Article
- A clinical pathway for the diagnosis of sesame allergy in children.The World Allergy Organization journal · 2022Article
- Insufficient reporting of experimental variables as a cause for nonreproducibility in animal physiology? A case study.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Review
- Metabolic mechanisms of acute proximal tubular injury.Pflugers Archiv : European journal of physiology · 2022Review
- Why and how we should join the shift from significance testing to estimation.Journal of evolutionary biology · 2022Article
- 'Invisible actors'-How poor methodology reporting compromises mouse models of oncology: A cross-sectional survey.PloS one · 2022Article
- Editorial : Reproducibility and replicability in science: A Sisyphean task.Journal of biosciences · 2022Article
- What have we learned?eLife · 2021Article
- Reprocessing 16S rRNA Gene Amplicon Sequencing Studies: (Meta)Data Issues, Robustness, and Reproducibility.Frontiers in cellular and infection microbiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
34526702What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.