Evidence map›Paper›PMID 34526677›Full record

ArticleEye (London, England)2022

Endocyclophotocoagulation combined with phacoemulsification in surgically naive primary open-angle glaucoma: three-year results.

Timothy E Yap, Piero Zollet, Salman Husein, Mohammad M M Murad, Sally Ameen, Laura Crawley, Philip A Bloom, Faisal Ahmed

Abstract read
In one paragraph

Article in Eye (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timothy E YapThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK.
Piero ZolletThe Imperial College Ophthalmology Research Group (ICORG), Imperial College London, London, UK.ORCID 0000-0002-5892-7533
Salman HuseinThe Imperial College Ophthalmology Research Group (ICORG), Imperial College London, London, UK.
Mohammad M M MuradThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK.
Sally AmeenThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK.
Laura CrawleyThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK.
Philip A BloomThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK.
Faisal AhmedThe Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK. faisal.ahmed5@nhs.net.ORCID 0000-0003-0015-6008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the safety and efficacy of endocyclophotocoagulation with phacoemulsification (phaco-ECP) in surgically naive, primary open-angle glaucoma (POAG).

methodsA retrospective case series of patients undergoing phaco-ECP between 2007 and 2017 at a single centre in London, UK. The primary outcome was intraocular pressure (IOP). Secondary outcomes were visual acuity, visual field global indices, topical medications and surgical complications. Failure criteria were: (1) IOP > 21 mmHg or <20% reduction at two consecutive visits, (2) IOP <5 mmHg and (3) further IOP-lowering surgery.

resultsEighty-three eyes from 83 patients were eligible. Pre-operatively, mean IOP (±SD) was 18.4 ± 5.2 mmHg. The mean number of topical agents (±SD) was 2.7 ± 0.9. Mean IOP (±SD) significantly reduced to 14.3 ± 4.7 at 1 year, 14.1 ± 4.0 at 2 years and 13.6 ± 3.7 at 3 years (p < 0.0001). Topical medications were significantly reduced to 1.3 ± 1.2 at 1 year, 1.7 ± 1.2 at 2 years and 1.8 ± 1.3 at 3 years (p < 0.0001). Annual IOP 'survival' was 70%, 54% and 45% at year 1, 2 and 3, respectively. Complications included uveitis (6%), macular oedema (2%), IOP spikes (1%) and corneal decompensation (1%) with no episodes of hypotony or retinal detachment. One patient underwent filtration surgery within 3 years (1%).

conclusionPhaco-ECP facilitates significant IOP lowering and reduction of medication burden in surgically naive POAG requiring cataract extraction. The procedure is relatively safe and without the use of implants and their associated risks.

Indexed as

CataractCataract ExtractionGlaucoma, Open-AnglePhacoemulsificationHumansIntraocular PressureRetrospective StudiesTonometry, OcularTreatment Outcome

Identifiers

PMID34526677
PMCPMC9499941

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