Evidence map›Paper›PMID 34526580›Full record

ArticleScientific reports2021

Decision making on vestibular schwannoma treatment: predictions based on machine-learning analysis.

Oliver Profant, Zbyněk Bureš, Zuzana Balogová, Jan Betka, Zdeněk Fík, Martin Chovanec, Jan Voráček

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Oliver ProfantDepartment of Auditory Neuroscience, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.
Zbyněk BurešDepartment of Cognitive Systems and Neurosciences, Czech Institute of Informatics, Robotics and Cybernetics, Czech Technical University, Jugoslávských partyzánů 1580/3, 160 00, Prague 6, Czech Republic. zbynek.bures@cvut.cz.
Zuzana BalogováDepartment of Otorhinolaryngology, 3rd Faculty of Medicine, University Hospital Královské Vinohrady, Charles University in Prague, Prague, Czech Republic.
Jan BetkaDepartment of Otorhinolaryngology and Head and Neck Surgery, 1st Faculty of Medicine, University Hospital Motol, Charles University in Prague, Prague, Czech Republic.
Zdeněk FíkDepartment of Otorhinolaryngology and Head and Neck Surgery, 1st Faculty of Medicine, University Hospital Motol, Charles University in Prague, Prague, Czech Republic.
Martin ChovanecDepartment of Otorhinolaryngology, 3rd Faculty of Medicine, University Hospital Královské Vinohrady, Charles University in Prague, Prague, Czech Republic.
Jan VoráčekFaculty of Management, Prague University of Economics and Business, Jindrichuv Hradec, Czech Republic.
Charles University · CZCzech Academy of Sciences · CZCzech Technical University in Prague · CZPrague University of Economics and Business · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decision making on the treatment of vestibular schwannoma (VS) is mainly based on the symptoms, tumor size, patient's preference, and experience of the medical team. Here we provide objective tools to support the decision process by answering two questions: can a single checkup predict the need of active treatment?, and which attributes of VS development are important in decision making on active treatment? Using a machine-learning analysis of medical records of 93 patients, the objectives were addressed using two classification tasks: a time-independent case-based reasoning (CBR), where each medical record was treated as independent, and a personalized dynamic analysis (PDA), during which we analyzed the individual development of each patient's state in time. Using the CBR method we found that Koos classification of tumor size, speech reception threshold, and pure tone audiometry, collectively predict the need for active treatment with approximately 90% accuracy; in the PDA task, only the increase of Koos classification and VS size were sufficient. Our results indicate that VS treatment may be reliably predicted using only a small set of basic parameters, even without the knowledge of individual development, which may help to simplify VS treatment strategies, reduce the number of examinations, and increase cause effectiveness.

Indexed as

Clinical Decision-MakingDisease ManagementMachine LearningAdultAgedDecision TreesFemaleHearingHearing TestsHumansMaleMiddle AgedNeuroma, AcousticReproducibility of ResultsROC CurveSupervised Machine Learning

Identifiers

PMID34526580
PMCPMC8443556
OpenAlexW3201312657

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.