ArticleCritical care (London, England)2021
Bedside estimates of dead space using end-tidal CO
Article in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The six phases of prolonged veno-venous extracorporeal membrane oxygenator support: a conceptual framework.Critical care (London, England) · 2026Review
- Arterial and end-tidal COBMC anesthesiology · 2026Observational
- Mechanical ventilation in ARDS: navigating the fine line with real-time monitoring.Critical care (London, England) · 2026Review
- Ultra-compact dual-channel integrated COMicrosystems & nanoengineering · 2024Article
- Flow-Field Inference for Turbulent Exhale Flow Measurement.Diagnostics (Basel, Switzerland) · 2024Article
- Diagnosis and Management of Acute Respiratory Failure.Critical care clinics · 2024Review
- Prognostic value of time-varying dead space estimates in mechanically ventilated patients with acute respiratory distress syndrome.Journal of intensive medicine · 2024Article
- Individualized estimation of arterial carbon dioxide partial pressure using machine learning in children receiving mechanical ventilation.BMC pediatrics · 2024Observational
- Agreement between arterial and end-tidal carbon dioxide in adult patients admitted with serious traumatic brain injury.PloS one · 2024Article
- Physiologic Markers of Disease Severity in ARDS.Respiratory care · 2023Review
- Prognostic value and immune landscapes of immunogenic cell death-related lncRNAs in hepatocellular carcinoma.Bioscience reports · 2023Article
- Interpretations of the Role of Plasma Albumin in Prognostic Indices: A Literature Review.Journal of clinical medicine · 2023Review
- Ventilation/perfusion mismatch is not the sole reason for hypoxaemia in early stage COVID-19 patients.European respiratory review : an official journal of the European Respiratory Society · 2022Article
- Therapeutic Effects of Inhaled Nitric Oxide Therapy in COVID-19 Patients.Biomedicines · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
purposeIn acute respiratory distress syndrome (ARDS), dead space fraction has been independently associated with mortality. We hypothesized that early measurement of the difference between arterial and end-tidal CO
methodsWe performed two separate exploratory analyses. We first used publicly available databases from the ALTA, EDEN, and OMEGA ARDS Network trials (N = 124) as a derivation cohort to test our hypothesis. We then performed a separate retrospective analysis of patients with ARDS using University of Chicago patients (N = 302) as a validation cohort.
resultsThe ARDS Network derivation cohort demonstrated arterial-ET difference, vasopressor requirement, age, and APACHE III to be associated with mortality by univariable analysis. By multivariable analysis, only the arterial-ET difference remained significant (P = 0.047). In a separate analysis, the modified Enghoff equation ((P
conclusionArterial to end-tidal CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.