ArticleJournal of orthopaedic surgery and research2021
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study.
Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Modifiable risk factors for perioperative hidden blood loss in unilateral biportal endoscopic surgery: a systematic review and meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Pooled it
- Does the number of drain tubes influence the formation of postoperative spinal epidural hematoma following biportal endoscopic unilateral laminotomy for bilateral decompression (BE-ULBD) in patients with two-level adjacent lumbar spinal stenosis? a prospective randomized study.Journal of orthopaedic surgery and research · 2025Trial
- A comparative study on hemostasis effect of different application methods and time of tranexamic acid in total hip arthroplasty.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Trial
- Short-term clinical efficacy of arthroscopic-assisted uni-portal spinal surgery- transforaminal lumbar interbody fusion for the treatment of single-segment low-grade degenerative lumbar spondylolisthesis: A retrospective cohort study.The Journal of international medical research · 2026Article
- Hidden Blood Loss in Full-Endoscopic Lumbar Decompression Compared with Biportal Endoscopic and Open Microscopic Surgery for Single-Segment Lumbar Stenosis.Journal of clinical medicine · 2026Article
- Hidden Blood Loss in Biportal Endoscopic Versus Traditional Open Spine Surgery: A Retrospective Comparative Study of Risk Factors and Clinical Relevance.Journal of clinical medicine · 2026Article
- Hidden blood loss in robot-assisted vs. conventional midline lumbar interbody fusion: a single-center propensity-score-matched cohort study.BMC surgery · 2026Article
- Advancements in unilateral biportal endoscopic lumbar interbody fusion: a narrative review.European journal of medical research · 2026Review
- Using machine learning algorithms to predict risk factors of heart failure after complete mesocolic excision in colorectal cancer patients.Scientific reports · 2025Article
- Comparison of Hidden Blood Loss in Biportal Endoscopic Spine Surgery and Open Surgery in the Lumbar Spine: A Retrospective Multicenter Study.Journal of clinical medicine · 2025Article
- Hidden blood loss in percutaneous endoscopic lumbar discectomy via the posterolateral approach.Joint diseases and related surgery · 2025Article
- Hidden blood loss and risk factors after percutaneous endoscopic transforaminal lumbar interbody fusion.Frontiers in surgery · 2025Article
- Risk factors for hidden blood loss in unilateral biportal endoscopic lumbar interbody fusion : a single-center retrospective study.BMC musculoskeletal disorders · 2024Article
- Comprehensive Analysis of UBE-Related Complications: Prevention and Management Strategies from 4685 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Article
- Does obesity and varying body mass index affect the clinical outcomes and safety of biportal endoscopic lumbar decompression? A comparative cohort study.Acta neurochirurgica · 2024Article
- Does the use of tranexamic acid intraoperatively reduce postoperative blood loss and complications following biportal endoscopic lumbosacral decompression?Journal of spine surgery (Hong Kong) · 2024Article
- Hidden blood loss in three different endoscopic spinal procedures for lumbar disc herniation.Annals of medicine and surgery (2012) · 2024Article
- Hidden blood loss and its risk factors in percutaneous vertebroplasty surgery for osteoporotic vertebral compression fractures.Archives of orthopaedic and trauma surgery · 2023Article
- Influencing factors of hidden blood loss after primary total hip arthroplasty through the posterior approach: a retrospective study.BMC musculoskeletal disorders · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases.
methodsThis multicentric retrospective study was conducted in 3 different medical centers between July 2020 and April 2021. Data of patients who underwent UBE surgery were extracted by electronic medical record system. The patient's demographic characteristics and blood loss-related parameters were recorded. We calculated the amount of HBL and explored the association between patient's characteristics and HBL using Pearson or Spearman correlation analysis. Multivariate linear regression analysis was conducted to identify independent risk factors of HBL.
resultsA total of 136 patients (55 females and 81 males, age range 43 to 74 years) were included in this study. A substantial amount of HBL (469.5 ± 195.3 ml, 57.6% of TBL, total blood loss) occurred following UBE surgery. Multiple linear regression analysis indicated that the risk factors of HBL were as follows: age (P = 0.000), number of fusion levels (P = 0.015), American Society of Anesthesiologists (ASA) classification (P = 0.046), surgery time (P = 0.017), patient's blood volume (PBV, P = 0.026), total blood loss (TBL, P = 0.001), postoperative (i.e., day 2 or 3) hematocrit (Hct, P = 0.034), Hct loss (P = 0.005), and fibrinogen (P = 0.028).
conclusionsA certain amount of HBL occurs in UBE surgery and cannot be ignored in daily clinical practice. The age, number of fusion levels, ASA classification, surgery time, PBV, TBL, postoperative Hct, Hct loss, and fibrinogen are independent risk factors for HBL.
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